hrp0092p3-326 | Late Breaking Abstracts | ESPE2019

Vitamin D and Type 1 Diabetes Mellitus in Children

Adji Tjahjono Harjoedi

Backgrounds: The understanding of the efects and role of vitamin D and its analogues in the functioning of body tissues, systems and organs has improved substantially over the last decade. The potential extra-skeletal role of vitamin D has been a rich area of interest and research over the last decade. Vitamin D deficiency has been implicated in a variety of chronic diseases, including bone mineral disease, autoimmunity, cancer, and diabetes. Many epidemiologi...

hrp0089p2-p037 | Bone, Growth Plate & Mineral Metabolism P2 | ESPE2018

Vitamin D Deficient (Nutritional) Rickets Presenting in Infancy

Prematilake Dilusha , Hashim Raihana , Kollurage Udeni , Atapattu Navoda

Background: Nutritional rickets is a disorder of defective chondrocyte differentiation and mineralization of the growth plate and osteoid due to vitamin D deficiency with or without low calcium intake in growing children. Maternal Vitamin D deficiency and exclusive breastfeeding without supplementation are the most frequent causes of rickets in the infancy. Vitamin D deficiency is still a problem in Sri Lanka in spite of sun shine throughout the year. We present a case series ...

hrp0092p1-174 | Bone, Growth Plate and Mineral Metabolism (1) | ESPE2019

The Optimal Dosage of Vitamin D Supplement for Vitamin D deficiency in Korean Children and Adolescents

Yang Seung , Hee Yi Kyung , Kim Eun Young , Hwang Il Tae

Purpose: Vitamin D deficiency (VDD) is very common nowadays in children as well as in adults, probably due to decreased exposure to sunlight. In Korea, the prevalence of VDD was 47% in teenage boys and 65% in teenage girls. However, the optimal dosage regimen for correcting deficiency is unknown. We investigate the change of serum 25(OH) vitamin D concentration according to the treatment dosage and duration in VDD.Methods...

hrp0084p1-18 | Bone | ESPE2015

Response to Vitamin D Replacement is Determined by Body Surface Area in Children with Vitamin D Deficiency

Chung In Hyuk , Kang Yu Sun , Yoo Eun-Gyong

Background: The serum 25-hydroxyvitamin D (25OHD) levels are known to be lower in obese children, probably due to sequestration of vitamin D in the adipose tissue. However, there is no consensus on the dose adjustment for vitamin D supplementation in obese children with vitamin D deficiency (VDD).Aims: To compare the response to vitamin D replacement in normal weight vs overweight children with VDD, and to investigate the determinant for increment of 25O...

hrp0092p3-309 | Late Breaking Abstracts | ESPE2019

Vitamin D Status Among Children and Adolescents in an Egyptian Cohort: Can we Predict Vitamin D Deficiency?

Karem Mona , Gamal Heiba Ebtehal , Kamel Noha , Gad Suzan

Background and Aim: Vitamin D plays a crucial role in skeletal and extra-skeletal physiology. It is essential for growth, development and health. It works as a paracrine and autocrine signaling molecule that affects nearly all systems in the body. Vitamin D deficiency (VDD) is prevalent in many countries in all age groups, and may be overlooked due to the variable clinical presentations according to age. This study was conducted to assess vitamin D status amon...

hrp0095s6.1 | Clinical management of calcium and phosphate disorders | ESPE2022

The effects of vitamin D supplementation on infant bone mass and body composition

Weiler Hope A.

Vitamin D supplementation is recommended for breastfed infants as primary prevention of vitamin D deficiency and nutritional rickets. Globally, the most commonly recommended dosage of vitamin D is 400 IU/day for healthy breastfed infants. Whether there are benefits of higher dosages of vitamin D to infant bone mass and body composition has been investigated. The objective of this presentation is to review the evidence from randomized controlled trials conducted in healthy term...

hrp0084p3-651 | Bone | ESPE2015

Vitamin D Level and Vitamin D Receptor DNA in Children with Diabetes Mellitus Studying Sequence Analyse and Polimorphism

Dogan Murat , Didin Muazzez , Bala Keziban , Kaba Sultan

Aım: İn this prospective planned study, it was aimed to study relationship between vitamin D level and vitamin D receptor gene polimorphism in patients with type l DM aged 0–18 years old.Methods and materials: We enrolled total 165 children in which 101 new and old diagnosed to WHO criterias TIDM patients from 0–18 years old and 64 chıldren as control group who were matched with gender and age. İn all cases serum Ca, P, PT...

hrp0084p3-906 | Fat | ESPE2015

Deficiency of 25-(OH) D-Vitamin in Adolescents with Obesity

Matveeva Mariia , Samoylova Julia

Objective: To evaluate the level of 25 (OH) D – vitamin in obese adolescents living in the South of Russia.Materials and method: We examined 20 obese adolescents with varying degrees of severity, aged 15.5±0.3 years, ten girls and boys. The comparison group consisted of ten healthy adolescents matched for age and sex. Obesity was calculated by BMI. Level of 25-(OH) D – vitamin was studied in the laboratory by ELISA (nmol/l). Furthermore, t...

hrp0084p1-2 | Adrenal | ESPE2015

Ontogeny of the Synchronisation between Adrenal Clock Genes, Adrenal Steroidogenesis-Related Genes and the Circadian Rhythm of the HPA Axis in Rats

Ruiz Silvia , Martins Clarissa , Castro Margaret , Antonini Sonir , Martinez Edson , Moreira Ayrton

Introduction: The circadian rhythmicity of the hypothalamic–pituitary–adrenal (HPA) axis depends on the synchronization of the clock molecular systems in the suprachiasmatic nucleus and in the adrenals. When and how this process occurs in the adrenal is unknown.Objective: To assess the ontogeny of daily variation of the expression of the adrenal clock genes (Clock, Arntl, Per1, Per2, Per3, Cry1, Cry2, Rora, and Nr1d1), steroid...

hrp0084p3-681 | Bone | ESPE2015

A Case of Vitamin D Deficient Rickets Showing Resistance to the Treatment of Active Vitamin D: Severe Calcium Deficiency Cause Vitamin D Resistance

Tanaka Hiroyuki , Hasegawa Kosei , Takatsuka Moe , Okahara Chika , Noguchi Yoshie , Takata Tsutomu , Ogura Kazuo

Case presentation: A 2-year-boy was referred tour hospital for the rickets. He was the first son between non-consanguineous parents and fed with breast milk. But after weaning, he was avoided from taking egg, dairy products including cow’s milk. He was also suffered from developmental delay and had strong food preference. He could take only two kinds of foods, steamed rice and soy bean product, tofu. X-ray findings showed typical rachitic change on long bone metaphysis. L...