hrp0092p2-102 | Diabetes and Insulin | ESPE2019

Flash Glucose Monitoring System Versus Blood Sugar Test Strips: Cost Comparison and Satisfaction During a Year in a Northern Spain Region

Bertholt Zuber Maria Laura , Freijo Martin Concepción , Naranjo Gonzalez Cristina , Palenzuela Revuelta Inmaculada , Mariscal Sara Pozas

Background: The flash glucose monitoring system (FGMS) has been a great advance in quality of life for patients diagnosed with type 1 diabetes (T1D). However, it is a more expensive method.Objectives: To describe the characteristics of the pediatric population (<18 years) diagnosed with T1D using FGMS, during one year in our community. To assess the degree of satisfaction and possible inconveniences. To evaluate the ...

hrp0092p3-238 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

Bilateral Testicular Atrophy and Normal Inhibin B level: A Paradoxal Clinical Finding For A Rare Biochemical Cause !

ESSADDAM Leïla , PIKETTY Marie , KALLALI Wafa , GUEDRI Rahma , GONZALEZ Laura , MATTOUSSI Nadia , POLAK Michel , BEN BECHER Saayda

Background: Testicular atrophy is a rare complication following inguinal hernia repair particularly in children<2 years and those with an undescended testis at highest risk> with an undescended testis. Inhibin B is secreted from the testis as a product of Sertoli cells, and has been suggested as a good marker for spermatogenesis. Its value is expected to be very low in children with bilateral testicular atrophyCase Report...

hrp0092p3-286 | Late Breaking Abstracts | ESPE2019

Alterations in Ambulatory Blood Pressure in Adolescents with Obesity

Diaz-Escobar Laura A , Lopez-Gonzalez Desiree , Garibay-Nieto Nayely , Villanueva-Ortega Erendira , Hernandez Ana Maria , Medeiros Mara

Introduction: Obesity is associated with comorbidities such as hypertension (HTN), and other alterations in blood pressure (BP) such as: masked hypertension and alterations in the circadian cycle variability, that only can be detect through ambulatory blood pressure monitoring (ABPM).A higher prevalence of masked hypertension has been reported in obese subjects, up to 4.3%. Also a loss in drop from mean daytime to mean night-time lev...

hrp0089rfc11.6 | Bone, Growth Plate &amp; Mineral Metabolism 2 | ESPE2018

Reference Values of Automated Bone Age and Bone Health Index for Mexican Children and Adolescents

Lora America Liliana Miranda , Espindola Montserrat Espinosa , Gonzalez Desiree Lopez , Loyo Mariana Sanchez-Curiel , Suarez Pilar Dies , Klunder Miguel Klunder

Background: BoneXpert is a software for automated measurement of bone age (BA) and radiogrammetry (bone health index). The precision error of the software for BA measure is smaller than the human rating error and the accuracy relative to the human routine ratings is 0.80 years. Differences in skeletal maturation between ethnicities have been reported, so it is important to have specific references for the own population.Objective: To present the automate...

hrp0089p3-p083 | Diabetes &amp; Insulin P3 | ESPE2018

Real–world Clinical Evolution of Type 1 Diabetes Patients on Twenty Years

Vergaz Amparo Gonzalez , Cuartero Beatriz Garcia , Salado Laura Sanchez , Escudero Veronica Sanchez , Lacalle Concepcion Garcia , Fernandez Marta Fernandez

Introduction: Type 1 diabetes mellitus (T1DM) is a chronic disease with important complications.Objective: Describe clinical characteristics, metabolic control and comorbidities of our pediatric diabetes population.Methods: T1DM patients diagnosed from 1996–2016 were included. Celiac and thyroid disease screening were analized.Clinical and biochemical data were compared during evolution. SPSS.21 for statistical study.<p cl...

hrp0089p2-p128 | Fat, Metabolism and Obesity P2 | ESPE2018

Leptin and Cytokines are Not the Best Markers for Metabolic S

Cuartero Beatriz Garcia , Vergaz Amparo Gonzalez , Lacalle Concepcion Garcia , Escudero Veronica Sanchez , Salado Laura Sanchez , Larramendi Carmen Hernando de

Introduction: Leptin, some cytokines and triglycéride/colesterol -HDL ratio (TG/C-HDL ratio) are markers of insulin-resistance in children and adolescents with overweight/obesity. Due to the high prevalence of this pathology it’s necessary to find and easy and better routinely marker that identify these patients in the outpatient clinic. Previous results demonstrated that TG/C-HDL ratio >2 was a better predictor of metabolic syndrome (sensitivity 100%; specificit...

hrp0089p2-p160 | Fat, Metabolism and Obesity P2 | ESPE2018

Obesogenic Environment and Their Influence on Adiposity on Mexican Children and Adolescents

Lopez-Gonzalez Desiree , Wells Jonathan , Reyes-Delpech Pamela , Avila-Rosano Fatima , Ortiz-Obregon Marcela , Gomez-Mendoza Frida , Clark Patricia

Introduction: Obesity is the main public health problem in Mexico. Several factors have been described as explanations, mainly: increased sedentarism and caloric intake. Such environment has been described as “obesogenic”. The aim of this study was to describe the relationship between the components of such obesogenic environment and the adiposity of Mexican children and adolescents.Methods: We carried a population-based cross-sectional study o...

hrp0089p3-p196 | GH &amp; IGFs P3 | ESPE2018

Main Discrepancies between Predicted and Observed Growth Responses with iGRO in Children Treated with GHr in Spain

Palma Cristina Mora , Martin Nerea Itza , Fernandez Julio Guerrero , Fresno Luis Salamanca , Bonis Ana Coral Barreda , Casado Isabel Gonzalez

Introduction: Growth prediction algorithms (i.e. iGRO), provide an estimate of a patients’ likely growth in the first year, and subsequent years, of GH treatment at a given dose, taking into account the patient’s combination of physical characteristics. Comparing a patient’s actual growth with their predicted growth after the first year of GH treatment, it is possible to determine whether the patient is responding to GH as expected (Index of responsiveness; IoR)...

hrp0086fc12.5 | Neuroendocrinology | ESPE2016

Abnormal Corticospinal Tract Decussation in Kallmann Syndrome due to ANOS1 (KAL1) Mutations: An Explanation of the Mirror Movements Frequently Observed in These Patients

Gonzalez-Briceno Laura , Sonnet Emmanuel , Guimiot Fabien , Laquerriere Annie , Kerlan Veronique , Salem Douraied Ben , Gunczler Peter , de Roux Nicolas

Background: Mirror movements (MM) are frequently associated to Kallmann syndrome (KS). They are mainly observed in patients with ANOS1 (KAL1) mutations. MM have never been reported in ANOS1 mutated females. A defect in the contralateral inhibition of the pyramidal tract has been proposed as the mechanism of MM in KS but never demonstrated.Objective and hypotheses: To investigate the molecular mechanism of a familial case of gonadotropic deficiency in whi...

hrp0086p2-p275 | Diabetes P2 | ESPE2016

Pancreatic Reserve and Metabolic Control of Type 1 Diabetes in a Cohort of Spanish Children and Adolescent

Laura Bertholt Zuber Maria , Cristina Luzuriaga Tomas Maria , Andres de Llano Jesus , Freijo Martin Concepcion , Naranjo Gonzalez Cristina

Objective: To evaluate the pancreatic reserve and metabolic control in our patient diagnosed of type 1 diabetes over the last 20 years.Method: Retrospective cohort study of all patients <15 years, diagnosed in our community between 01/01/1995 and 31/12/2014. Variables: gender, age at diabetes debut, age at study, c-peptide after stimulation with glucagon at debut and 1 month after, HbA1c at debut, 1 month, 1 year, 2 years, 5 and 10 years of debut. Co...