hrp0094p2-218 | Fat, metabolism and obesity | ESPE2021

Impact of overweight and obesity in pediatrics. Metabolic syndrome and its components

San Martin Amaya , Vilella Leyre , Garcia Casales Zurine , Calvo Ariadne , Rocha C , Sarasua Miranda Ainhoa , Diez-Lopez Ignacio ,

The current lifestyle, with a diet increasingly removed from the Mediterranean diet, together with the habitual sedentary lifestyle, is associated with many of the so-called non-communicable diseases, such as the metabolic syndrome. Every day these pathologies are more frequent in pediatrics, so this study has tried to establish the prevalence of metabolic syndrome and its components in overweight and obese children and assess its impact. METHODS A descriptive study has been c...

hrp0097p2-166 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2023

Value of antimullerian hormone (AMH) in the diagnosis of precocious puberty: revaluation of the covid-19 post-pandemic cohort

Diez-Lopez Ignacio , Aurora Vilella San Martín Leyre , Sarasua Miranda Ainhoa , San Martin Orayen Amaia , Maeso Mendez Sandra

During the pandemic, an increase in the cases of premature thelarche consultations was observed. Our group published a series in 2021 of 75 cases. This effect could have been caused by an increase in body fat mass in girls, suggesting a “trigger effect” in the activation of the gonadal axis, causing an increase in the number of cases of early puberty (SEEP Oviedo 2022). AMH has been correlated as a predictor of the moment of menarche (doi: 10.1515/jpem-2014-0521)</...

hrp0086p1-p479 | Fat Metabolism and Obesity P1 | ESPE2016

Hepatic Steatosis and Cardiovascular Risk in Overweight Children: Preliminary Results of the Study EFIGRO

Diez-Lopez Ignacio , Sarasua Ainhoa , Medrano Maria , Arenaza Lyde , Rodriguez-Vigil Beatriz , Tobalina Ignacio , Larrarte Eider , Perez-Asenjo Javier , Labayen Idoia

Introduction: The accumulation of fat in the liver is a serious complication of childhood obesity seems to be associated with cardiometabolic risk.Objective: To examine the association between fat accumulation in the liver and cardiovascular risk factors in overweight children.Material and methods: In the study 68 children/as (51.4% girls) were overweight or obese (defined according to the classification criteria of the Internation...

hrp0092p3-320 | Late Breaking Abstracts | ESPE2019

EpiPEG-PreMeb Study: Chemerina Plasmatic and Metabolic Syndrome Relation at SGA Childrens

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , Leniz Asier , Fernandez-Quintela Alfredo , Portillo Maria Puy , Macarulla-Arenaza Maria Teresa , Lorente-Blazquez Isabel

The objective of this study has been the analysis of plasma chemistry in a group of children born SGA at the University Hospital of Álava- Txagorritxu and biochemical parameters related to the metabolic syndrome.Material and Methods: In a cohort of 27 subjects sub (13 boys and 14 girls) from the epiPEG-PreMeb study, a blood sample at 3, 12 and 24 months of life it was extracted. Biochemical parameters s and measured by automated and...

hrp0089p3-p240 | Growth &amp; Syndromes P3 | ESPE2018

The Expression of Cytokines in SGA Children Throughout Lactation Allows to Characterize Early the Type of Cath-up

Diez-Lopez Ignacio , Sarasua Ainhoa , delHoyo Marta , Lorente Isabel , Segura Raquel Gomez de , Picon Minerva , Leniz Asier , Fernandez Alfredo , Puy-Portillo Maria

Up to 50% of children born SGA at 2 years have not made a correct catch up (by excess or defect), with repercussions on size, metabolic and cardiovascular alterations, DM, etc. The Project has developed a prospective cohort of SGA and seeks to study phenotypic, BQ and genetic differences that explain their different behavior.Material and methods: We study live births of single pregnancies in our Hospital during 2012–2014, and are classified accordin...

hrp0086p1-p639 | Growth P1 | ESPE2016

Spanish ECOS Study Analysis: Socioeconomic Data, Adherence and Growth Outcomes with Case Studies

Rodriguez-Arnao Maria , Sanchez Amparo Rodriguez , Lopez Ignacio Diez , Fernandez Joaquin Ramirez , de la Vega Jose Bermudez , Ballano Virginia , Nieto Jenny Alvarez , Koledova Ekaterina

Background: The ECOS observational study in Spain (NCT01376921) aims to evaluate adherence to r-hGH therapy prescribed via the easypod™ electromechanical auto-injector device and to analyse factors that may influence adherence in paediatric patients. Easypod™ administers pre-set doses of Saizen® r-hGH and stores accurate records of each dose and injection taken, which can then be shared with the HCP for evaluation of the patient’s adherence.<...

hrp0086p2-p876 | Syndromes: Mechanisms and Management P2 | ESPE2016

Project Epi Peg-Premeb. Clinical Situation of a Person Born SGA Followed from Birth Cohort. GLOBAL Causes and Clinical Situation of Partial Birth Cohort and 12 Months

Diez-Lopez Ignacio , Sarasua Ainhoa , Hoyo Marta del , Lorente Isabel , de Segura Raquel Gomez , Perez Dorleta , Picon Minerva , Macarulla Maria Teresa , Rodriguez Bittor

Up to 50% of children born SGA to 2 years have not made a proper catch up (by excess or defect), with repercussions in size, metabolic and cardiovascular disorders, DM, etc. epiPEG-PreMeb project to study during their first two years of life.Goals:: Establish a SGAcohort for monitoring, evaluation catch-up, and analysis of medium-environmental and social factors. To study the influence of these variables on clinical, laboratory and metabolic profiles. So...

hrp0082p3-d1-882 | Perinatal and Neonatal Endocrinology | ESPE2014

Project Episga: PreMeb Presentation, Subject Recruitment, and Initial Data

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , Hoyo-Moracho Marta , Lorente-Blazquez Isabel , Lorente Raquel Gomez de Segura , Campos Dorleta Perez , Rodriguez-Rivera Victor Manuel , Macarulla-Arenaza Maria Teresa

Background: Up to 50% SGA did not do a proper catch up (for over/under) and may have implications in size, metabolic, cardiovascular. Arises: epiSGA – PreMeb Project. Global approach to study.Objective: Create clinical cohort of SGA for monitoring, assessment catch-up, use GHRH requirements, environmental/social factors and variables influence on clinical, laboratory and metabolic profiles in order to progress in the knowledge of natural history. Pr...

hrp0082p3-d2-889 | Perinatal and Neonatal Endocrinology (1) | ESPE2014

Evolution and Epidemiological Assessment of the Influence of Sociological Variables of Children Born SGA in the Last Decade in Basque Country

Diez-Lopez Ignacio , Hoyo-Moracho Marta , Sarasua-Miranda Ainhoa , Lorente-Blazquez Isabel , Rodriguez-Rivera Victor Manuel , Macarulla-Arenaza Maria Teresa , de Segura Lorente Raquel Gomez , Campos Dorleta Perez

Background: Although the theoretical impact of small in weight and/or size at birth (<2 SDS for EG) is 3–5% (3.5% in the Basque Country (source: Local Government) the socio-economic situation in our country has conditioned a change in its l although 50% at 2 years did not do a proper catch up (by excess or defect) with potential impact on future size and metabolic complications, cardiovascular require specific monitoring.Objective: To assess soc...

hrp0084p3-929 | GH &amp; IGF | ESPE2015

Biochemical Profiles Differentials by SGA Children Catch Up

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , del Hoyo-Moracho Marta , de Segura Raquel Gomez , Perez-Campos Dorleta , Mararulla-Arenaza Maria Teresa , Rodriguez-Rivera Victor Manuel

Background: SGA cohort study in analytical and metabolic variables at 3 and 12 months of age with somatométrica situation.Material and methods: Live births in singleton pregnancies in our hospital during 2012–2014, PEG were studied according EG and weight/height (Spanish Tablas 2008). Tours are conducted at 0, 3, 6, 9, 12 months, with measurements of weight, height and perimeter. Blood samples are obtained at least fasting discussed 4h and exce...