hrp0094p2-89 | Bone, growth plate and mineral metabolism | ESPE2021

Clinical Profile of Parathyroid Adenoma in Children and Adolescents: A single-center experience

Kizilcan Cetin Sirmen , Siklar Zeynep , Ozsu Elif , Aycan Zehra , Ceran Aysegul , Karaca Seda Erisen , Senyazar Gizem , Berberoglu Merih ,

Introduction: Parathyroid adenoma (PRAD) is less common than in adulthood, but its morbidity is higher in children. The typical presentation is incidentally discovered as asymptomatic hypercalcemia. We aimed to evaluate the clinical characteristics of PRAD and our clinical experience since the early disease is often asymptomatic.Method: From 2010-2020, all children diagnosed with PRAD at our institution ...

hrp0097p1-419 | Bone, Growth Plate and Mineral Metabolism | ESPE2023

Evaluation of the pediatric patients diagnosed with secondary osteoporosis

Singin Berna , Donbaloğlu Zeynep , Barsal Çetiner Ebru , Aydın Behram Bilge , Ünver Tuhan Hale , Parlak Mesut

Objective: Secondary osteoporosis has a high rate of accompanying chronic diseases. We aimed to review the clinical and laboratory features, underlying causes, Dual Energy X-ray Absorptiometry (DEXA) results before and after treatment of patients diagnosed with secondary osteoporosis and to determine the relationship between this condition and fracture rates.Methods: This study was designed as a single-center, descriptiv...

hrp0097p1-358 | Pituitary, Neuroendocrinology and Puberty | ESPE2023

Do gonadotropin releasing hormone analogues increase the total body fat mass and body mass index in girls with idiopathic central precocious puberty?

Donbaloğlu Zeynep , Singin Berna , Barsal Cetiner Ebru , Aydin Behram Bilge , Bedel Aynur , Tuhan Hale , Parlak Mesut

Aim: Gonadotropin-releasing hormone analogues (GnRHa) are widely used in the treatment of idiopathic central precocious puberty (ICPP) cases due to premature maturation of the hypothalamus-pituitary-gonad axis. The effect of GnRHa therapy on body weight and fat distribution is controversial in the literature. We aimed to examine the anthropometric measurements and body composition analysis of the girls with ICPP and to investigate the effect of related factors...

hrp0095p1-55 | Diabetes and Insulin | ESPE2022

Screening for disordered eating behaviours and associated factors in children and adolescents with type 1 diabetes

Barsal Çetiner Ebru , Donbaloğlu Zeynep , Singin Berna , Aydın Behram Bilge , Bedel Aynur , Parlak Mesut , Ünver Tuhan Hale

Introduction and Purpose: Patients with type 1 diabetes mellitus must be extremely concerned with what they eat and their insulin dose as part of their treatment. Therefore, the risk of eating disorders increases in this patient group. This study, it was aimed to determine the disordered eating behaviors of patients with Type 1 DM and to evaluate the results of the general demographic characteristics, diabetes care behaviors, and quality of life scale that whi...

hrp0095p1-475 | Fat, Metabolism and Obesity | ESPE2022

The Impact of Acute Exercise on 12,13-Dihydroxy-9Z-Octadecenoic Acid (12,13-DiHOME) Levels in Male Adolescents with Obesity

Ercan Oya , Gurup Aybüke , Tarçın Gürkan , Yakal Sertaç , Turan Hande , Şahinler Ayla Sibel , Boztürk Güngör Zeynep

Aim: 12,13-dihydroxy-9Z-octadecenoic acid (12,13-diHOME) is a lipokine secreted from brown adipose tissue, and it is shown to have positive effects on dyslipidemia. Acute exercise have been shown to lead to an increase in its secretion. It was aimed to investigate the relation of 12,13-diHOME with obesity, exercise and dyslipidemia for the first time in the adolescent age group.Methods: This is a prospective study includ...

hrp0095p1-396 | Thyroid | ESPE2022

A rare cause of acquired von Willebrand factor deficiency: Primary hypothyroidism due to autoimmune thyroiditis

Dağdeviren Çakır Aydilek , Yıldız Yıldırmak Zeynep , Eren Simge , Mısırlı Özdemir Ebru , Özdemir Mustafa , Ucar Ahmet

In children, autoimmune thyroiditis is often diagnosed with signs and symptoms such as goiter, short stature, and constipation. Delayed diagnosis of hypothyroidism may result in atypical signs and symptoms at presentation, depending on the severity of hypothyroidism. Von Willebrand disease (vWD) is the most common bleeding disorder caused by the quantitative or qualitative deficiency of von Willebrand factor (vWF). Acquired vWD (avWD) is a disorder characterized by low levels ...

hrp0095p1-591 | Thyroid | ESPE2022

Evaluation of Permanent and Transient Congenital Hypothyroidism in Cases Referred from National Neonatal Screening Program

Donbaloğlu Zeynep , Çetinkaya Semra , Aycan Zehra , Karacan Küçükali Gülin , Şakar Merve , Savaş Erdeve Şenay

Objective: The incidence of congenital hypothyroidism (CH) has increased worldwide. Lowering cut-off in screening programs has led to an increase in the rate of transient CH. We aimed to evaluate the rates of permanent and transient CH in cases referred from the screening program and to investigate the clinical and laboratory factors to predict the transient CH.Methods: 109 cases referred from the screening program to ou...

hrp0092p1-402 | Pituitary, Neuroendocrinology and Puberty (2) | ESPE2019

Evaluation of Brain Mri Lesions in 381 Girls with Central Precocious Puberty

Helvacioglu Didem , Guran Tulay , Kirkgoz Tarik , Atay Zeynep , Abali Zehra Yavas , Eltan Mehmet , Kaygusuz Sare Betul , Seven Tuba , Gurpinar Busra , Turan Serap , Bereket Abdullah

Central precocious puberty (CPP) in girls is a diagnosis increasingly made by the Pediatric Endocrinologists worldwide. Although it is most frequently of idiopathic origin, magnetic resonance imaging (MRI) of the brain is recommended to rule out organic lesions causing CPP. However, controversy exists regarding the age limits for routinely performing MRI in girls with CPP.Objective: To evaluate the outcome of brain MRI in girls diagnosed...

hrp0092p3-134 | Fetal, Neonatal Endocrinology and Metabolism (to include Hypoglycaemia) | ESPE2019

Persistant Hypoglycemia in Children: Hyperinsulinemia

Direk Gül , Tatli Zeynep Uzan , Şiraz Ülkü , Çiçek Dilek , Hatipoğlu Nihal , Kendirci Mustafa , Kurtoğlu Selim

Congenital hyperinsulinemia occurs due to inappropriate insulin secretion from beta cells of the pancreas. It is the most common cause of resistant and recurrent hypoglycemia in neonates and infants and the threatment is very difficult. Although the incidence is reported as 1/50000, it is seen more frequently in consanguineous countries. Patients may present with lethargy, nourishment, irritability and seizures. If it is not treated, severe hypoglycemia may result in severe ne...

hrp0089p3-p044 | Bone, Growth Plate & Mineral Metabolism P3 | ESPE2018

Clinical Evaluation of Eight Patients with Parathyroid Adenoma

Direk Gul , Uzan Tatli Zeynep , Nur Hepokur Merve , Gul Şiraz Ulku , Akin Leyla , Hatipoğlu Nihal , Kendirci Mustafa , Kurtoğlu Selim

Objective: According to the etiology of hyperparathyroidism, it is divided into primer and secondary (uremic). It usually develops due to CaSR mutation in the infancy period. On the other hand, it usually emerges secondary to a parathyroid adenoma in adolescents. Parathyroid adenomas seen in childhood are commonly associated with familial multiple neoplasia syndromes (MEN). Patients may present with bone pain, proximal myopathy, fractures, renal stone, pancreatitis or they can...