ESPE Abstracts

Aim: Acanthosis nigricans (AN) is the most important skin complication of obesity. In our study, the relationship of acanthosis nigricans and vitamin D levels was evaluated in children.

Methods: Obese children aged between 6 and 18 years old, who were examined in the pediatric endocrinology outpatient clinic, were included. The patients’ anthropometric measurements and laboratory results and vitamin D levels were recorded.

Results: Eighty nine obese children were evaluated. The mean age of the cases was 11,51±3,04 years old. Of the cases, 58.4% were female (n = 52) 41.6% (n = 37) were male, 59,6% of them were pubertal (n = 53) while 40,6 of them were prepubertal (n = 36). In 60,9 % of cases (n = 53) AN was determined. In the cases, Low vitamin D level was found in 83.1% (n = 74) of cases. Obese children with AN have lower levels of vitamin D (11,59±4,33; 14,83±7,52 P = 0.013) and significantly higher insulin levels and HOMA-IR P = 0.005, P = 0.001). Obese children who have low vitamin D levels have higher HOMA-IR (5.43±2.20; 4.04±1.72 P = 0.035).

Conclusions: In our study, a relationship between acanthosis nigricans and vitamin D levels were detected. Acanthosis nigricans is a skin sign that can be easily detected by clinician. It is an important and easy-to-detect dermatosis that helps determine patients at risk of metabolic complications and related with low vitamin D levels in obese children.