ESPE Abstracts

Introduction: The main reason for Newborn screening (NBS) for congenital adrenal hyperplasia (CAH) is to prevent adrenal insufficiency that can lead to life-threatening conditions. On the other hand, screening programmes are not always sensitive and effective enough to detect the disease. We aimed to evaluate the specificity, sensitivity and efficiency of the national NBS for CAH in Lithuania.Methods: retrospective study...

Background: Public health research shows that the prevalence of obesity is increasing rapidly not only among adults, but especially among adolescents and children. Obese children and adolescents are at risk of early chronic complications such as cardiovascular diseases, non-alcoholic fatty liver disease (NAFLD), type 2 diabetes mellitus, various types of tumors, orthopedic problems, serious psychological and neurological problems.<strong...

Background: According to World Health Organization, balanced diet and regular physical activity is the key to maintaining a healthy lifestyle.Objective and hypotheses: The aim of this study was to evaluate lifestyle habits of the healthcare personnel in Latvia.Method: Data about eating habits, physical activity, duration of sleep and other lifestyle factors were collected from medical students, medical residents and specialized doc...

Introduction: Abnormal levels of lipids and lipoproteins are recognized as a prominent cardiovascular risk factor associated with increased morbidity and mortality. In many studies childhood obesity has been shown to be associated with increased levels of total cholesterol (TH), triglycerides (TG), LDL-cholesterol, and decreased levels of HDL-cholesterol.Objective: The aim of this study was to evaluate the risk of dyslipidemia (abnormal levels of all of ...

Background: Insulin resistance for adolescents with obesity takes up a central role in the development of metabolic comorbidities, especially of type 2 diabetes.Objective and hypotheses: The aim of this study was to compare anthropometric data, apolipoprotein B, glucose, insulin level and HOMA-IR coefficien between genders.Method: Data about anthropometric parameters, blood samples, 6-min walk test (6MWT), eating habits and physica...

Background: Recombinant human GH (rhGH) is normally administered as a daily s.c. injection. NNC0195-0092 is a reversible albumin-binding GH derivative developed with the aim of reducing clearance and thereby extending the exposure. It has previously been demonstrated that NNC0195-0092 is well tolerated in healthy subjects with the potential for once weekly administration.Objective and hypotheses: In this trial NNC0195-0092 was administrated subcutaneousl...