ESPE Abstracts

Introduction: Robinow syndrome is a rare autosomal recessive and autosomal dominant disorder affecting the whole skeletal system. Autosomal recessive robinow syndrome is characterized by shortness of the long bones and vertebra anomalies. Less than 200 cases of autosomal recessive robinow syndrome have been reported in the literature.Case: The newborn was referred to pediatric endocrine clinic for disorder of penis devel...

Background: Experience with oral desamino-D-arginine-8-vasopressin lyophilisate (OLD) for central diabetes insipidus (CDI) in children with CNS malformations is limited.Objective and hypotheses: We aimed to assess the efficacy of oral use of OLD in children with CDI.Methods: Clinical, laboratory, and imaging characteristics of twenty-five children with CDI treated with OLD were eva...

Aim: This experimental study is to investigate the effects of excessive fructose consumption on body weight, omental fat, insulin resistance, lipid profile and lipid peroxidation.Materials-Methods: In this study, 18 mature, albino, male Sprague Dawley rats (aged 8 weeks, weighing 200–220 g) were included in our study. They were fed ad libitum, housed in pairs in steel cages, and kept in a temperature-controlled env...

Background: Vitamin D deficiency has been shown to increase fatty liver disease (FLD) incidence in patients with obesity (4,5). This study aim ed to determine the effects of a single dose of 300,000 IU cholecalciferol on insulin resistance and fatty liver disease (FLD) in children with obesity with vitamin D deficiency.Methods: In this clinical study, 128 patients aged 8-18 years with obesity and vitamin D deficiency wer...

Background: Hyperuricemia has been found to be associated with non-alcoholic fatty liver disease (NAFLD).Aim: The aim of this study was to evaluate whether allopurinol affects the course of experimental NAFLD in rats.Study Design: Mature, albino Sprague Dawley rats were fed water containing 30% fructose without ethanol for up to 8 weeks. After demonstration of steatosis in the 8th week, either allopurinol or saline was administered...

Background: Few studies have investigated the association between the development and progression of diabetic retinopathy and autoimmune processes resulting from HLA genotype and the relationship of these genes with islet autoantibody status.Objective: This study explored how serum diabetes autoantibodies are related to the development of early diabetic retinopathy (EDR) in children with type 1 diabetes mellitus (T1DM).<...

Objective: To compare the serum 25-hydroxy Vitamin D [25(OH)D] concentrations in children and adolescents with obesity with and without hepatosteatosis, and investigate the relationship between serum 25(OH)D concentrations and severity of hepatosteatosis. We also aimed to assess the effect of vitamin D treatment after 6 months on hepatosteatosis and liver biochemistry.Methods: One hundred thirty-three obese patients with...