hrp0092p1-432 | Thyroid (2) | ESPE2019

Levothyroxine Effect on Thyroid Volume in Children with Autoimmune Hashimoto Thyroiditis (AHT) Presenting Subclinical (SH) or Overt (Oh) Hypothyroidism

Leka-Emiri Sofia , Petrou Vassilios , Evangelopoulou Cathrine , Vakaki Marina , Fotinou Aspasia , Vlachopapadopoulou Elpis , Michalacos Stefanos

Objectives: Assess thyroid volume in relation to TSH and FT4 at diagnosis of AHT and 2.9 years of follow up in children with SH or OH.Methods: wo hundred one children (155 girls) with AHT were divided according to TSH and FT4 levels [SH-FT4 >1.0 ng/dl: Group 1: TSH: 5-7.5 mU/l, Group 2: TSH: >7.5 mU/l, OH: Group 3: TSH>7.5 mU/l and FT4 ≤1.0ng/dl]. Mean L-T4 dose is reported in µg/Kg/day. Thyroid...

hrp0089p1-p074 | Diabetes & Insulin P1 | ESPE2018

Catheter Site Selection and Anthropometric Measurements at Subjects with Type 1 Diabetes and Continuous Subcutaneous Insulin Infusion

Xatzipsalti Maria , Vakaki Marina , Mentesidou Lida , Kourti Afroditi , Patouni Konstantina , Choundala Anna , Stamogiannou Lela , Vazeou Andriani

Introduction: The selection of the insulin catheter length for pump T1D users is based mainly on age and though different sites for insertion have been suggested, it is not clear what the ideal site is according to each person’s body type and subcutaneous fat.Aid: Aid of the study is to identify the proper sites for insulin catheter insertion according to subcutaneous fat and anthropometric characteristics.Methods: Study group...

hrp0089p3-p392 | Thyroid P3 | ESPE2018

Hashitoxicosis:a Rare Diagnosis in Childhood

Vlachopapadopoulou Elpis Athina , Stergiotis Stefanos , Dikaiakou Eirini , Kafetzi Maria , Vakaki Marina , Fotinou Aspasia , Michalacos Stefanos

Aim: To highlight the diagnosis of Hashitoxicosis and its distinction from Graves’s disease. Subjects with Hashimoto’s thyroiditis are often euthyroid or may experience subclinical or true hypothyroidism. However, in 5 to 10% of children, a transient phase of hyperthyroidism, called Hashitoxicosis, may occur.Patients-Methods: Three female patients, were referred at the ages of 61/12, 96/12 and 12...

hrp0086p1-p247 | Diabetes P1 | ESPE2016

Which is the Best Site for Catheter Placement in Young Children with Type 1 Diabetes (T1D) and CSII?

Xatzipsalti Maria , Vakaki Marina , Patouni Konstantina , Kourti Afroditi , Mentesidou Lida , Choundala Anna , Stamoyannou Lela , Vazeou Andriani

Background: Few data exist for young children regarding the proper site for insulin catheter insertion for pump (CSII) users.Objective and hypotheses: To evaluate the proper site for catheter insertion in very young children (<8 year old) with T1D and CSII.Method: The study comprised 10 children [7 females, median age 4.43 years (range 2.3–7.18), median disease duration 1.65 years] with T1D who were on CSII. Ultrasound mea...

hrp0086p2-p960 | Thyroid P2 | ESPE2016

FNA: A Gold Standard in the Diagnosis of Thyroid Nodules in Children after Chemotherapy

Leka-Emiri Sofia , Petychaki Fotini , Petrou Vassilis , Vakaki Marina , Pourtsidis Apostolos , Vlachopapadopoulou Elpida , Michalakos Stefanos

Background: Non Hodgkin lymphoma (NHL) is the fourth most common malignancy in childhood. Chemotherapy constitutes the first line treatment and may cause several endocrine side effects (growth retardation, hypergonadotrophic hypogonadism, bone mass loss and rarely secondary malignancy). In total of 1–2% of children may harbour thyroid nodules. The most common risk factors are: irradiation, female sex, iodine deficiency, puberty and past medical history of thyroid disease....

hrp0094p2-401 | Sex differentiation, gonads and gynaecology or sex endocrinology | ESPE2021

Two sisters with primary hypergonadotrophic hypogonadism, pubertal progress and deletion of 61.5MB of Χq21.33q28 region

Dikaiakou Eirini , Vlachopapadopoulou Elpis Athina , Papoulidis Ioannis , Manolakos Emannouil , Vakaki Marina , Michalacos Stefanos

Objective: To present the novel finding of hypergonadotropic hypogonadism, pubertal progress and molecular alterations in two sisters with variable phenotype.Case Presentation: Two Greek sisters were investigated. The eldest was referred for investigation of short stature, at the age of 9 and 5/12 years. There was no positive family history for short stature. Physical examination revealed no dysmorphic features, and she was prepubertal according to Tanne...

hrp0097p2-199 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2023

Adolescent girl with premature ovarian insufficiency due to X-chromosome deletion

Dikaiakou Eirini , Georgiadis Ilias , Koutrouveli Eleni , Vakaki Marina , Grigoriadou Maria , Kolialexi Aggeliki , Vlachopapadopoulou Elpis-Athina

Objective: Premature ovarian insufficiency (POI) is rare in adolescents, most commonly caused by genetic defects or cytotoxic therapy. The aim is to present the case of an adolescent girl with normal pubertal progress and irregular menstrual cycle, followed by amenorrhea.Case presentation: A 15 9/12-years-old girl presented because of lack of menses for the previous 21 months. She reported that she had menarche at the ag...

hrp0097p1-187 | Thyroid | ESPE2023

Thyroid nodules and differentiated thyroid carcinoma in children and adolescents. Experience of a tertiary pediatric endocrinology center in Greece.

Dikaiakou Eirini , Leka Sofia , Kosteria Ioanna , Athanasouli Fani , Vakaki Marina , Geli Myrsini , Sevaslidou Ioanna , Papadopoulou Katerina , Vlachopapadopoulou Elpis-Athina

Objectives: The aim of this study was to report on the frequency and describe the clinical characteristics of the ones diagnosed as thyroid cancer among all suspicious nodules diagnosed in the pediatric endocrinology department and to compare the findings with recent published literature.Methods: Retrospective study during the last 5 years. Patients aged <18 years, with suspected thyroid nodule malignancy, according t...

hrp0097p1-397 | Thyroid | ESPE2023

Increased frequency of Grave’s Disease during COVID-19 pandemic

Kosteria Ioanna , Athanasouli Fani , Dikaiakou Eirini , Leka-Emiris Sofia , Papadopoulou Katerina , Fakiolas Stefanos , Kafetzi Maria , Vakaki Marina , Vlachopapadopoulou Elpis-Athina

Introduction: Increased frequency of Grave’s disease (GD) has been reported both in adults and youth during the COVID-19 pandemic. Aim: To compare the frequency of GD prior and during the COVID-19 pandemic.Methods: Retrospective analysis of children diagnosed with GD over the last 13 years in our Department.Results: A total of 22 children (31.8% boys) with a mean age of 10.55...