hrp0097p1-143 | Pituitary, Neuroendocrinology and Puberty | ESPE2023

Comparison of the Test Accuracy of a Subcutaneous Gonadotropin-Releasing Hormone Agonist (Triptorelin Acetate) vs. Intravenous Gonadorelin in the Diagnosis of Central Precocious Puberty

Ahn Jungmin , Rim Jeong Hwal

Purpose: In the diagnosis of central precocious puberty (CPP), the gonadotropin-releasing hormone (GnRH) stimulation test using intravenously injected gonadorelin is the gold standard. However, gonadorelin is not always readily available. In this study, the diagnostic accuracy of a test based on the GnRH agonist triptorelin acetate (triptorelin) was compared to that of the classical gonadorelin-based test in the diagnosis of CPP in girls.<p class="abstext"...

hrp0092p1-407 | Pituitary, Neuroendocrinology and Puberty (2) | ESPE2019

No Association Between Serum Level of NPTX 1 and MKRN3 in Central Precocious Puberty

Rim Jeong Hwal , Tae Hwang Il

Abstract: Background: Makorin ring finger protein 3 (MKRN3) is most common genetic cause of central precocious puberty (CPP) and associated with the initiation of puberty. Although its actual function is veiled. Recent study reported MKRN3 interacted with and suppressed neural pentraxin-1 precursor (NPTX1) activity via polyubiquitination during early puberty in mice.Objective: The aim of this study was t...

hrp0097p2-204 | Thyroid | ESPE2023

A Case of Neonatal Thyrotoxicosis born to mother after thyroidectomy for Grave’s disease

Rim Jeong Hwal , Young Kim Joo

Neonatal thyrotoxicosis is rare and most of the cases are secondary to maternal Graves’ disease. It is usually transient, but can be associated with significant morbidity and mortality if not recognized promptly and treated adequately. We report a case of a 20-day-old female infant who developed thyrotoxicosis with irritability, tachycardia, and relatively poor weight gain. She was born to a mother who took levothyroxine during pregnancy after undergoing a thyroidectomy ...

hrp0097p1-463 | Fat, Metabolism and Obesity | ESPE2023

Association between lean mass and metabolic syndrome risk in Korean children and adolescents

Suk Shim Young , Sang Lee Hae , Rim Jeong Hwal , Sub Lim Jung , Soon Hwang Jin

Introduction: Skeletal muscle plays a crucial role in glucose disposal, and studies have shown a positive relationship between muscle mass and insulin sensitivity. However, an elevated lean mass has also been associated with metabolically adverse outcomes. This study aimed to evaluate the association between the risk of metabolic syndrome (MetS) and lean mass using dual-energy X-ray absorptiometry (DXA) in a nationally representative sample from the Korea Nati...

hrp0097p1-70 | Fat, Metabolism and Obesity | ESPE2023

Association of Serum Uric Acid Levels with Metabolic Syndromes in Children and Young Adolescents

Suk Shim Young , Seo Young-Jun , Sang Lee Hae , Rim Jeong Hwal , Sub Lim Jung , Soon Hwang Jin

Purpose: We investigated uric acid reference values and their association with cardiometabolic risk among children and adolescents using the Korea National Health and Nutrition Examination Survey (KNHANES).Methods: A total of 2,462 participants, aged 10-18 years, from the KNHANES 2016-2018 were included.Results: Serum uric acid (SUA) levels varied with sex and age. In male subjects...