ESPE Abstracts

ESPE Abstracts

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Page 10 of about 208 results

hrp0084p3-885 | Fat | ESPE2015

Is vitamin D Important Player in Hepatosteatosis in Childhood Obesity?

Ozsu Elif , Topcu Feyza Nur , Tepe Derya Acar

Background and aim: Childhood obesity is one of the most serious public health problem. Obesity-related complications such as hepatic steatosis or type 2 diabetes can now be monitored even during early childhood. The aim of the study was to examine the relationship between vitamin D levels and obesity with hepatosteatosis (HS) in children.Methods: A total of 128 children with obesity were included in this study. HS was diagnosed using ultrasonography. HS...
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hrp0095t12 | Section | ESPE2022

Assessment of non-alcoholic fatty liver disease with non-invasive indices in adolescents with polycystic ovary syndrome

Context: Polycystic ovary syndrome (PCOS) is a complex disorder affecting women from adolescence until menopause. PCOS in adolescent years shares common features with clinical presentation in adulthood, including the adverse metabolic profile. Non-alcoholic fatty liver disease (NAFLD) is a spectrum of hepatic changes, from liver steatosis to severe inflammation and fibrinogenesis.Objective: To assess NAFLD in an adolesce...
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hrp0095p1-87 | Fat, Metabolism and Obesity | ESPE2022

Thyroid Disfunctions During Pediatric Obesity: Possible Role in Obese Children with Insulin Resistance

Salvatore Guercio Nuzio , D'Isanto Livio

Introduction: Pediatric obesity (PO) is associated with hormonal dysfunctions contributing to an increased risk of cardiovascular disease and diabetes. Among these risks, thyroid disfunctions (TD) are the most common. The ethio-pathogenetic mechanisms underlying TD are not well known and include an adaptive response to a higher energy intake, hyperleptinemia, peripheral resistance to thyroid hormones, increased pro-inflammatory cytokines. Pediatric prevalence ...
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hrp0095p1-273 | Fat, Metabolism and Obesity | ESPE2022

An adult-based genetic risk score for hepatic fat associates with liver and lipid traits in Danish children

Huang Yun , E. Stinson Sara , Bæk Juel Helene , A.V. Lund Morten , Aas Holm Louise , E. Fonvig Cilius , Grarup Niels , Pedersen Oluf , Christiansen Michael , Krag Aleksander , Stender Stefan , Holm Jens-Christian , Hansen Torben

Background and Aim: Several genetic variants associating with hepatic fat content in adults have been identified in genome-wide association studies. Their effects in children remain unclear. This study aimed to test the effect of genetic variants known to associate with hepatic fat in adults, individually and combined as a genetic risk score (GRS), on cardiometabolic traits, and to investigate the predictive ability of the GRS for hepatic steatosis in children...
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hrp0092rfc4.2 | Fat Metabolism and Obesity Session | ESPE2019

Circulating Exosomal miRNAs in Children's Nonalcoholic Steatohepatitis and the Correlation with Serum Transaminase and Uric Acid

Zhou Xuelian , Huang Ke , Ni Yan , Yuan Jinna , Liang Xinyi , Lin Hu , Dong Guanping , Fu Junfen

Background: The incidence of non-alcoholic fatty liver disease (NAFLD) in children increased rapidly paralleled with the global burden of obesity and diabetes. Although most patients are nonalcoholic fatty liver (NAFL), once progress to nonalcoholic steatohepatitis (NASH), the risk of liver fibrosis and cirrhosis increase significantly. However, the pathogenesis of NAFLD, especially how NAFL progress to NASH is still unclear. Exosomal miRNAs have attracted att...
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hrp0092p1-342 | Fat, Metabolism and Obesity (2) | ESPE2019

Can Increased First Hour Glucose Concentration in OGTT Be a New Indicator in Projecting Metabolic Profile?

Sahin Nursel Muratoglu , Yilmaz Aslihan Arasli , Özalkak Servan , Aycan Zehra

Aim: Recent studies have shown that the first hour glucose concentration of ≥155 mg / dL in the oral glucose tolerance test (OGTT) in adults with normal glucose tolerance (NGT) may be a strong marker for the development of diabetes, and also an increase in subclinical inflammation, insulin resistance, dyslipidemia and serum transaminases. These results indicate that adults with NGT have increased risk of developing cardiovascular disease and non-alcoholi...
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hrp0092p1-384 | Growth and Syndromes (to include Turner Syndrome) (2) | ESPE2019

Pubertal Induction Amongst Girls with Turner Syndrome: A Review of Changing Practice Over 10 Years.

Elechi Hassan Abdullahi , Law James , Benson Joanna , Denvir Louise , Randell Tabitha , Sachdev Pooja

Background: Pubertal induction with incremental doses of oestrogen replacement is an important component of care offered to hypogonadal patients with Turner Syndrome (TS). Low dose oral ethinylestradiol (EE) has been extensively used in the UK but natural 17-β oestradiol (more physiological, cheaper and easily monitored in blood) is becoming increasingly popular.We undertook this audit to compare the efficacy and acceptability of...
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hrp0092p3-185 | Multisystem Endocrine Disorders | ESPE2019

Final Height and Endocrine Complications in Patients with β-Thalassemia Intermedia: (TI) Our Experience in Non-Transfused Versus Infrequently Transfused Patients and Correlations with Liver Iron Content

TAWFIK SOLIMAN ASHRAF , Yassin Mohamed , Yassin Khadra , Abdulla Mohammad , De Sanctis Vincenzo

We evaluated the final height and the endocrine complications encountered in young adult patients with Thalassemia Intermedia (TI) followed at Hematology Section, Doha (Qatar) in relation to the liver iron content (LIC) in non-transfused versus infrequently transfused TI patients.Patients and Methods: This retrospective cohort study was performed on 28 young adults with TI who were randomly selected from the Hematology clinic, National C...
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hrp0092p3-188 | Multisystem Endocrine Disorders | ESPE2019

Endocrinopathies and Linear Growth in Adolescents with β-Thalassemia Intermedia in Relation to Liver Iron Content

TAWFIK SOLIMAN ASHRAF , Yassin Mohamed , adel ashraf

We evaluated the linear growth and some endocrine function in 10 adolescents with Thalassemia Intermedia (TI) followed at Hematology Section, Doha (Qatar) in relation to the liver iron content (LIC).Patients and Methods: This retrospective cohort study was performed on 10 adolescents with TI who were randomly selected from the Hematology clinic, National Centre for Cancer Care and Research, Hamad Medical Corporation of Doha (Qatar). 8 in...
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hrp0089p1-p110 | Fat, Metabolism and Obesity P1 | ESPE2018

Lipid Accumulation Product is a Predictor of Non-alcoholic Fatty Liver Disease in Childhood Obesity

Ozcabi Bahar , Demirhan Salih , Akyol Mesut , Akay Hatice Ozturkmen , Guven Ayla

Objectives: We aimed to evaluate the performance of lipid accumulation product (LAP) to predict non-alcoholic fatty liver disease (NAFLD) in obese children.Methods: Eighty obese chidren (39 girl) were included in this study (6–18 years). Height, weight, body mass index (BMI), waist circumference (WC), puberty stage, blood pressure (n=28), fasting glucose, fasting insulin, HOMA-IR, alanine aminotransferase (ALT), aspartate aminotransferase (...
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