hrp0089p1-p167 | Growth & Syndromes P1 | ESPE2018

Improved Mental and Motor Development During 3 Years of GH Treatment in Very Young Children with Prader-Willi Syndrome

Donze Stephany , Damen Layla , Mahabier Eva , Hokken-Koelega Anita

Context: Infants and toddlers with Prader-Willi Syndrome (PWS) have a mental and motor developmental delay. Short-term data suggest a positive effect of growth hormone (GH) on mental and motor development in infants and children with PWS. There are, however, no longer-term results about the effects of GH treatment on mental and motor development.Objective: To investigate the longer-term effects of GH on psychomotor development in infants and toddlers wit...

hrp0086fc15.6 | Late Breaking | ESPE2016

Type 1 Diabetes Associated Serum Insulin-Like Growth Factor I (IGF-I) Reference Values in Children and Adolescents

Oberg Daniel , Salemyr Jenny , Ortqvist Eva , Juul Anders , Bang Peter

Background: The disturbance of the GH-IGF-axis in type 1 diabetes (T1DM) with low circulating IGF-I, GH hypersecretion, and hyperinsulinemia, which may be associated with high tissue IGF-I, have implications on long-term vascular complications.Objective and hypotheses: To establish disease, sex and age related serum IGF-I reference values for children with T1DM and test the hypothesis that IGF-I SDS is lower in T1DM than in healthy controls and negativel...

hrp0084p2-203 | Adrenals | ESPE2015

Autoimmune Encephalitis – A Newly Recognised Clinical Manifestation of Autoimmune Polyendocrine Syndrome Type 1?

Ferenczova Juliana , Vargova Veronika , Krysl David , Banoova Erika , Sadova Eva

Background: Autoimmune polyendocrine syndrome (APS) type 1 is a rare autosomal recessive disease. The classic features are chronic mucocutaneous candidiasis, hypoparathyroidism and adrenocortical failure. Several non-classic presentations of the disease has been described over the last few years. Authors present a case of 14-year old girl with a new serious non-classic presentation.Case presentation: Patient was diagnosed with a mucocutaneous candidiasis...

hrp0084p2-458 | Growth | ESPE2015

Sleep Apneas in Silver Russell Syndrome: A Constant Finding

Giabicani Eloise , Boule Michele , Galliani Eva , Netchine Irene

Background: Imprinting disease such as Prader-Willi syndrome (PWS) are associated with pathological sleep due to central and obstructive apneas. No data are available concerning Silver Russell syndrome (SRS) but most patients describe day asthenia and snoring. These patients also often present with maxillo-facial malformations.Aims and objectives: We wanted to characterise sleep in SRS and evaluate GH therapy possible effect on it....

hrp0084p3-880 | Fat | ESPE2015

Healthcare Professionals’ Perception of Overweight in Preschool-aged Children

Bocca Gianni , Corpeleijn Eva , Broens Jasper , Stolk Ronald , Sauer Pieter

Background: Childhood obesity is still increasing worldwide. Early recognition of overweight or obesity in children by healthcare professionals is of utmost importance, allowing interventions to start at a young age.Objective and hypotheses: We studied whether healthcare professionals adequately perceive preschool children’s overweight and whether this is influenced by their own BMI.Method: Healthcare professionals received a ...

hrp0094p2-228 | Fat, metabolism and obesity | ESPE2021

Lifestyle habits, consumption of non-nutritive sweeteners and obesity in students and young adults’ population in Latvia.

Roze Zane , Perle Eva , Krisane Iveta Dzivite , Grope Ilze ,

Background: Since 1975 the prevalence of obesity has tripled. As one of the habits of a healthy lifestyle is to reduce the fast sugars in our meals, the supply of non-nutritive sweeteners in the food supply has increased by offering sweeter meals without extra calorie intake.Objectives: To explore the characteristics of students and young adults’ lifestyle habits and consumption of non-nutritive sweeteners and their...

hrp0097p1-69 | Fat, Metabolism and Obesity | ESPE2023

Difference of nafld frequency between younger and older children with obesity

Stanikova Daniela , Vitariusova Eva , Kosnacova Jana , Cierna Iveta , Stanik Juraj

Background: Non-alcoholic Fatty Liver Disease (NAFLD) is a frequent complication of obesity in both adults and children and there is an alarming increase in prevalence of both. Studying of risk factors for NAFLD in children and adolescents might help to select vulnerable groups to start an early intervention.Objectives: The aim of our study was to detect the prevalence of NAFLD in pediatric obese patients (0-18.9 years, ...

hrp0097p2-56 | Bone, Growth Plate and Mineral Metabolism | ESPE2023

Monogenic Diabetes (MODY) in Adolescents and Personalized Treatment.

Mozzato Chiara , Meneghin Alice , Monti Elena , Trevisson Eva , Guazzarotti Laura

Pathologically elevated serum levels of fibroblast growth factor-23 (FGF23), a bone-secreted hormone that regulates phosphorus homeostasis, result in renal phosphate wasting leading to rickets or osteomalacia. Patterns leading to FGF23 excess are still unknown. Recently, FGF23 elevated rickets has been associated with epidermal nevus syndrome, designating the cutaneous skeletal hypophosphatemia syndrome (CSHS). The clinical picture is not completely defined as, to date, only a...

hrp0097p2-32 | Fat, Metabolism and Obesity | ESPE2023

The prevalence and risk factors of non-alcoholic fatty liver disease in obese and normal weight children in Latvia

Gailite Jurgita , Petrosina Eva , Gardovska Dace , Dzivite-Krisane Iveta

Background: Public health research shows that the prevalence of obesity is increasing rapidly not only among adults, but especially among adolescents and children. Obese children and adolescents are at risk of early chronic complications such as cardiovascular diseases, non-alcoholic fatty liver disease (NAFLD), type 2 diabetes mellitus, various types of tumors, orthopedic problems, serious psychological and neurological problems.<strong...

hrp0082p1-d1-201 | Reproduction | ESPE2014

The Effect of 17β-Estradiol on Uterine Volume in Young Women with Turner Syndrome: a 5-Year Randomized Controlled Clinical Trial

Cleemann Line , Holm Kirsten , Fallentin Eva , Moller Nini , Kristensen Bent , Skouby Sven Oluf , Leth-Esbensen Per , Jeppesen Eva Mosfeldt , Gravholt Claus

Background: The majority of Turner syndrome (TS) girls need exogenous estrogen treatment to induce normal uterine growth. The optimal estrogen treatment protocol has not been determined.Objective and hypotheses: To compare the effect of two different dosing regimens of oral 17β-estradiol on uterine size with the hypotheses that most girls with TS would benefit from a higher dose.Method: A double-blind 5-year randomized control...