hrp0084p3-864 | Fat | ESPE2015

A Systemic Approach for the Management of the Program Entitled ‘Development of a National System for the Prevention and Management of Overweight and Obesity in Childhood and Adolescence in Greece’

Kassari Penio , Papaioannou Panagiotis , Charmandari Evangelia

Background: The prevalence of obesity has increased dramatically in Greece in the last two decades, and more than 35% of children and adolescents are currently overweight or obese. Prevention could be the key strategy for controlling the current epidemic of obesity.Objective and hypotheses: Prevention is the main scope of the Program entitled ‘Development of a National System for the Prevention and Management of Overweight and Obesity in Childhood a...

hrp0089p3-p001 | Adrenals and HPA Axis P3 | ESPE2018

Congenital Adrenal Hyperplasia: A Patient’s Perspective, a Mother’s Story

Landa Allison

Statement of the Problem: Studies suggest that psychosocial factors – in addition to physical barriers – work to impair fertility and successful childbirth in women with Congenital Adrenal Hyperplasia. This includes a reluctance to consult medical professionals as to the scope of the problem and possible solutions. This was the case with Allison Landa, who was not even successfully diagnosed with CAH until the age of 30 due to parental negligence and the terror of di...

hrp0084p1-40 | Diabetes | ESPE2015

Efficacy and Safety of a Fixed Combination of Insulin Degludec/Insulin Aspart in Children and Adolescents with Type 1 Diabetes

Battelino Tadej , Deeb Larry , Reiter Panagiota Diamantopoulou , Greve Tina Maria , Klingensmith Georgeanna , Kocova Miriana , Kovarenko Margarita , Shehadeh Naim

Background: Insulin degludec/insulin aspart (IDegAsp) is the first soluble co-formulation that combines two insulin analogues.Aims and objectives: To assess the efficacy and safety of IDegAsp administered once-daily (OD) plus meal-time IAsp for remaining meals in controlling glycaemia as assessed by change in HbA1c from baseline in a paediatric population.Methods: A 16-week, 1:1, open-label, parallel group, randomised, t...

hrp0089p3-p154 | Fat, Metabolism and Obesity P3 | ESPE2018

Relation of Screen-Time (Phone-Computer-TV-Online Games) and Physical Activity with Childhood Obesity

Yılmaz Mehmet Mustafa , İlarslan Nisa Eda Cullas , Gunay Fatih , Yılmaz Ozlem , Ates Funda Seher Ozalp , Kose Serdal Kenan , Atalay Semra , Bilir Pelin

Objective: Sedentary lifestyle obviously increases the risk of obesity. Reduced physical activity and increased screen-time seem to act as major determinants of the rapid increase of childhood obesity. Prevention of obesity is easier and more practical in comparison with treatment of obesity and its complications. Treatment of childhood obesity not only carries positive biopsychosocial consequences for the child but also serves as an important public health issue by preventing...

hrp0092p2-123 | Fat, Metabolism and Obesity | ESPE2019

Overweight, Obesity and Hypertension among Adolescents – the Impact of Immigration and a Acculturation

Hamiel Uri , Bendor Cole , Bardugo Aya , Berr Zivan , Derazne Estela , Tzur Dorit , Grossman Ehud , Afek Arnon , Twig Gilad , Pinhas-Hamiel Orit

Aims: The migration from one cultural milieu to another has drastically increased cardiovascular risk factors and disease rates. We studied the prevalence of overweight and obesity, and hypertension among adolescents of Ethiopian origin who immigrated to Israel, as well as on Israeli born children of Ethiopian origin.Methods: Adolescents aged 16-19 years, who were medically examined prior to mandatory military service in...

hrp0086p2-p278 | Diabetes P2 | ESPE2016

Childhood Type 1 Diabetes (T1D) Management with e-learning through Self-educational Tools

Bibal Cecile , Laure Castell Anne , Aboumrad Brigitte , Lucchini Philippe , Bougneres Pierre

Background: Children with type 1 diabetes (T1D) and their parents need personalized i) information about the disease and glucose homeostasis and ii) knowledge and guidelines about diet and insulin therapy.Objectives: To set a complete educational program that allows children with T1D to improve disease management and daily life.Methods: Education modules were written and trained with children and parents at outpatient visits. Each ...

hrp0082p1-d3-224 | Reproduction (2) | ESPE2014

Test on Kisspeptin Levels in Girls with Idiopathic Central Precocious Puberty and its Significance

Yang Yu , Xiong Xiang-Yu , Yang Li , Xie Li-Ling , Huang Hui

Objective: This paper is aimed to explore the significance of plasma kisspeptin level in diagnosis and therapeutic evaluation through the detection of kisspeption level of girls diagnosed with idiopathic central precocious puberty (ICPP) before treatment and after 6-months of treatment and girls with simple premature thelarche (PT).Methods: A total of 70 girls including 24 girls diagnosed with ICPP, 21 girls with PT and 25 normal girls were enrolled. ELI...

hrp0092p1-30 | Diabetes and Insulin | ESPE2019

Effects of Glypican-4 Protein on INS1E Cell Viability and Insulin Signalling

Buhl Joseph , Garten Antje , Richter Sandy , Kiess Wieland , Penke Melanie

Background: Glypican-4 is a heparan sulphate proteoglycan. In addition to a membrane-bound glypican-4, a soluble form exists. Human and rodent adipose tissue were identified as source of circulating glypican-4. Glypican-4 serum levels are associated with obesity and insulin resistance, as in type 2 diabetes (T2D). Because of its positive effect on insulin sensitivity, glypican-4 might play a role in the development of obesity, insulin resistance, and T2D. We a...

hrp0089rfc12.1 | Diabetes and Insulin 2 | ESPE2018

Use of Acid-Suppressivemedications During Infancy and Early Childhood and Its Association with Type 1 Diabetes

Menon Sruthi , Umapathi Krishna Kishore , Thavaman Aravind , Bora Geetanjali , Davis Ajuah

Background: Type 1 diabetes is a multifactorial, immune mediated disease whose incidence has been increasing worldwide. These changes in prevalence cannot be explained by genetic susceptibility alone and several lifestyle changes have been linked to the rising incidence including obesity, diet and mode of delivery. Many of these environmental factors influence the composition of the gut microbiome which interacts with the immune system as well as affects gut permeability, thus...

hrp0089rfc14.2 | Multisystem Endocrine Disorders | ESPE2018

British Society for Paediatric Endocrinology and Diabetes Peer Review of Specialised Paediatric Endocrinology Services in the UK - Evaluation of the Outcomes

Schulga Joihn , Mitchell Heather , Musson Pauline , Shaw Nick , Patel Leena

Introduction: The BSPED Peer review programme was initiated in 2011 to provide a regular cycle of independent impartial professional assessment, against quality standards for Specialised Paediatric Endocrine Services (SPES) in the UK.1 We present here an evaluation of the outcomes from the first review cycle completed in 2017.Methods: We examined pre-review self-assessments (4–6 weeks before a site visit by the Peer Review team) and post-...