ESPE Abstracts

Background: Accurate and differential diagnosis of preococious puberty (PP) have some important challenges. Many parameters have used to diagnose pubertal diseases so far. However LH-RH stimulation test is considered as a gold standard procedure, ıt has some difficulties in practise.Objective: We aimed to set a newly proposed clinical and laboratory finding-based diagnostic scoring in the differential diagnosis of preoccious puberty and premature te...

Introduction: GnRH analogues common used in precocious puberty are highly effective agents. The drug dose and injection frequency should be designed for each case. However these agents are common well tolerated, some rare adverse effects may be occur. We present a case of frequent leuprolid acetate injections-related sterile abscess.Case: The case was 16-month-old boy. He had rapid growth, big penis, and excessive pubic hair. These symptoms have appeared...

Objective: There have no been studies enough about thyroid volumes of obese and adolescent children. In this study, we purposed comparing of thyroid volumes in respect of anthropometric, biochemical, metabolic parameters in following groups: Overweight, obese, morbid obese, and healthy children.Method: Two groups were compared: The first group consisted of 190 children whose BMIs are above the 85th percentile. The second group was 90 children with normal...

Background: Graves’ disease is a rare autoimmune thyroid disease that characterized by hyperthyroidism, diffuse goitre and ophthalmopathy. It generally involved both lobes of the thyroid, unilateral involvement was rare.Case report: A 18 year old girl presented with weakness, alopecia, menstruel irregularity. In physical examination moist skin, increased pulse rate (116/min) and enlargement of the right lobe of the thyroid was determined. Her blood ...

Aim: This study aimed to investigate retrospectively the demographic, clinical and laboratory data of patients followed up for hypothyroidism and to determine the insidance of persistent hypothyroidism.Materials and Methods: A total of 209 patients with hypothyroidism were included retrospectively in this study. Demographic data, clinical features, laboratory results, thyroid volume, follow-up time, treatment drug were recorded. These patients were divid...

Objective: Vitamin D plays an important role in hyperlipidemia, cardiovascular disease risk, and glucose/insulin metabolism. The aim of this study is; to investigate the relationship between serum vitamin D levels and metabolic profiles of children with T1DM, atherogenic index, and cardiovascular disease risk.Materials and Methods: T1DM patients were included in the study retrospectively. Anthropometric and clinical measurements, biochem...

Aim: Acanthosis nigricans (AN) is the most important skin complication of obesity. In our study, the relationship of acanthosis nigricans and vitamin D levels was evaluated in children.Methods: Obese children aged between 6 and 18 years old, who were examined in the pediatric endocrinology outpatient clinic, were included. The patients’ anthropometric measurements and laboratory results and vitamin D levels were rec...

Introduction: PTEN Hamartoma Tumor Syndrome (PHTS) is a rare disease with dominant inheritance characterized by benign (hamartoma) and malignant tumors (breast, endometrium, thyroid). Mutations in the tumor suppressor gene phosphatase and tensin homologue (PTEN) gene are responsible for the etiology.Objective: In this case report, we present an 11-year-old male who was being monitored due to follicular thyroid cancer, an...

Introduction: Autoimmune polyglandular syndrome type 1 (OPS1) is characterized by chronic mucocutaneous candidiasis, hypoparathyroidism and autoimmune adrenalitis. The mutations in the localized autoimmune regulator gene (AIRE) at 21q22.3 present the etiological cause.Objective: In this case report, two siblings case who were diagnosed with OPS1 with different clinical findings except classic triad were presente...

Introduction: 17β-hydroxysteroid dehydrogenase type 3 (17βHSD3) enzyme deficiency is a rare cause of 46 XY disorder of sexual development. It is inherited autosomal recessively and clinical phenotype is highly heterogeneous and depends on the mutation severity. Conversion of androstenedione to testosterone deteriorates due to lack of enzyme.Objective: In this case report, we present a case who was born en...