hrp0082p3-d3-725 | Diabetes (2) | ESPE2014

Differences in Pubertal Development and Anthropometry Between Normal Population and Type 1 Diabetic Child at Debut in Spain

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , Sanchez-Antonio Sonia , Lorente-Blazquez Isabel

Background: The deterioration caused DMtipo1 anthropometric and pubertal development. With intensive treatment, improved HbA1c and less microvascular complications should be similar to normal population.Objective: To study the pubertal development in our population with DM1 and final somatometric variables reached in relation to the normal population.Material and methods: Retrospective study of DM1A debut from diagnosis to final he...

hrp0094p1-149 | Sex Endocrinology and Gonads B | ESPE2021

Query By Telarquia: Has there been an increase due to the SARS-COV19 pandemic?

Vilella Leyre Aurora , Martin Amaia San , Maeso Sandra , Sarasua-Miranda Ainhoa , Diez-Lopez Ignacio ,

Have a real increase in precocious and advanced puberty with COVID19? Retrospective observational analytical study in which we compared the incidence of first consultations made by early thelarchies between the months of March to December 2019 and between March and December 2020 at the Pediatric Endocrinology(PE)consultation in our hospital, and the increase in diagnosis of precocious puberty (PP)and advanced puberty (PA) in the cases evaluated for this reason, with the aim of...

hrp0097p1-266 | Fat, Metabolism and Obesity | ESPE2023

Abdominal fat measured with nutritional ultrasound as a risk screening for non-alcoholic hepatic steatosis (NASH) in obese children

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , Maeso Mendez Sandra , Garcia Casares Zuriñe , Erika Calvo Saez A

NASH is an increasingly relevant finding in the pediatric population affected by obesity. In adults, its evolution from this steatosis to fibrosis and its correlation with metabolic syndrome is increasingly significant. The existence of a rapid and validated screening tool in consultation would be very useful.Main objective: To evaluate if the measurement of intraperitoneal fat measured through nutritional ultrasound, allows the diagnosi...

hrp0097p2-81 | Growth and Syndromes | ESPE2023

Small for age gestational: puberty status, metabolism and growth of an epipeg-premeb clinical cohort at 7-9 years after onset.

Diez-Lopez Ignacio , Sarasua Miranda Ainhoa , Maeso Mendenz Sandra , Etxebarria Aurrekoetxea Maialen

Objective: Observe in children born SGA the relationship that the different variables have in the evolution towards metabolic syndrome, adrenarche and/or early/advanced pubarche or short stature and treatment with GH.Material and Methods:A retrospective observational study analyzing in SGA children at birth (n=103) and who are currently between 7-9 years of age, variables such as: sex; “Catch UP&r...

hrp0095p1-163 | Pituitary, Neuroendocrinology and Puberty | ESPE2022

Stress and Hyperprolactinemia: Can a Stimulation Test be Used to Evaluate?

Makosiej Nicholas , Jeanette Haugh , Ghanny Steven , Aisenberg Javier

Background: Prolactin is a peptide hormone produced by the anterior pituitary gland. Hyperprolactinemia can be caused by stress, but pathological causes of hyperprolactinemia could be due hypothyroidism, medications or hypothalamic/pituitary tumors. It is important to differentiate between the causes of hyperprolactinemia. The best way to accomplish this is via a rest test. One way to accomplish this would be to measure prolactin levels as a part of a hormone ...

hrp0095p2-125 | Fat, Metabolism and Obesity | ESPE2022

Effects of confinement due to COVID-19 in the child population of Álava on vitamin D status, weight and body composition

and body composition weight , Aguirre-Lopez Leixure , Puy Portillo-Baquedano Mari , Fernandez-Quintela Alfredo , Leniz-Rodríguez Asier , Diez-Lopez Ignacio

The coronavirus disease (COVID-19) pandemic brought with it a state of alarm as of March 14, 2020, which implied a restriction on the mobility of the general population and home confinement. One of the main concerns raised by isolation was the substantial reduction in energy expenditure due to children spending more time sitting or participating in activities that involve very low rates of energy expenditure, such as watching television, managing the different networks social ...

hrp0082p2-d2-425 | Growth Hormone (1) | ESPE2014

Electronic Devices and Single-Dose Dispensing Systems GH are the Most Efficient and Less Loss of Drug

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , Elizalde Miriam Miriam , Lorente-Blazquez Isabel , Minguez Cristina , Martinez-Martinez Carlos

Background: Several pharmaceutical formulations marketed GHRH, were being restricted in their choice occasions. Three display groups: single-dose, pre-filled pens/vials and electronic devices, self-injection systems. The choice may contribute to a greater or lesser adherence and a difference in the final cost of treatment (drug loss), attributable to the device itself or presentation. Presentations that require reconstitution device load, partial doses or stop in Pen contribut...

hrp0082p2-d3-447 | Growth Hormone (2) | ESPE2014

Efficacy, Adherence, and Cost Study According to Pathology and Treatment Devices in Children Treated with GHRH

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , Elizalde Miriam Miriam , Lorente-Blazquez Isabel , Minguez Cristina , Martinez-Martinez Carlos

Background: Currently there are three distinct groups of GH devices: single dose (JM), preloaded pen/vial (VM) systems and electronic devices (DE) autoinjector systems. The choice could determine a greater or lesser adherence and thus influence the final treatment efficacy.Objective: Comparison of the therapeutic efficacy as measured by growth rate (VC), IGF1 as a function of various clinical variables, indicating GH and device used.<p class="abstext...

hrp0094p2-218 | Fat, metabolism and obesity | ESPE2021

Impact of overweight and obesity in pediatrics. Metabolic syndrome and its components

San Martin Amaya , Vilella Leyre , Garcia Casales Zurine , Calvo Ariadne , Rocha C , Sarasua Miranda Ainhoa , Diez-Lopez Ignacio ,

The current lifestyle, with a diet increasingly removed from the Mediterranean diet, together with the habitual sedentary lifestyle, is associated with many of the so-called non-communicable diseases, such as the metabolic syndrome. Every day these pathologies are more frequent in pediatrics, so this study has tried to establish the prevalence of metabolic syndrome and its components in overweight and obese children and assess its impact. METHODS A descriptive study has been c...

hrp0097p2-166 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2023

Value of antimullerian hormone (AMH) in the diagnosis of precocious puberty: revaluation of the covid-19 post-pandemic cohort

Diez-Lopez Ignacio , Aurora Vilella San Martín Leyre , Sarasua Miranda Ainhoa , San Martin Orayen Amaia , Maeso Mendez Sandra

During the pandemic, an increase in the cases of premature thelarche consultations was observed. Our group published a series in 2021 of 75 cases. This effect could have been caused by an increase in body fat mass in girls, suggesting a “trigger effect” in the activation of the gonadal axis, causing an increase in the number of cases of early puberty (SEEP Oviedo 2022). AMH has been correlated as a predictor of the moment of menarche (doi: 10.1515/jpem-2014-0521)</...