hrp0084p1-51 | Diabetes | ESPE2015

Distribution of Obesity Indices Among European Preschool Children and Associated Risk Factors: The ToyBox-Study

Galcheva Sonya , Lateva Mina , Iotova Violeta , Bourdeaudhuij Ilse De , Cardon Greet , Androutsos Odysseas , Kulaga Zbigniew , Socha Piotr , Moreno Luis , Koletzko Berthold , Manios Yannis , Group ToyBox-study

Background: Childhood obesity is a serious health problem, related to an increased risk of adult morbidity and mortality. Evidence indicates that central adiposity increases this risk to a higher degree compared to the general obesity indices.Objective and hypotheses: To evaluate the distribution of anthropometric obesity indices among preschool children aged 3.5–5.5 years, from six European countries, and to examine their associations with certain ...

hrp0084p3-873 | Fat | ESPE2015

Sex Differences in the Pubertal Response to High-Fat Diet

Freire-Regatillo Alejandra , Argente-ARizon Pilar , Diaz Francisca , Barrios Vicente , Arevalo Angeles , Argente Jesus , Garcia-Segura Luis Miguel , Azcoitia Inigo , Chowen Julie A

Background: It is well known that ingestion of a high fat diet (HFD) can induce rapid weight gain and metabolic imbalances. However, males and females are not equally susceptible to these effects. Furthermore, an individual may be more prone to gain weight during specific developmental periods.Aims and objectives: We aimed to analyse the response to the acute exposure to a HFD during pubertal/adolescent period and to determine whether males and females r...

hrp0097p1-43 | Diabetes and Insulin | ESPE2023

Our experience in neonatal diabetes mellitus: clinical and molecular characterisation

Salamanca Fresno Luis , Gomes Porras Mariana , Pozo Román Jesús , Del Pozo Ángela , Rodríguez Jiménez Carmen , González Casado Isabel , Campos Barros Ángel

Introduction: Neonatal Diabetes Mellitus (NDM) is characterised by severe hyperglycaemia, usually diagnosed in the first 6 months of life. Genetic diagnosis helps distinguishing between its different causes and between transient (TNDM) and permanent (PNDM) forms, with repercussions on the therapeutic approach and follow-up.Aim: Clinical and molecular characterisation of a series of NMD cases under endocrinological follow...

hrp0097p1-567 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2023

An International Delphi Based Study For Developing A Core Outcome Set For Hypospadias Surgery

Leunbach Tina. , Yankovic Francisca , Springer Alexander , Wisniewski Amy , Burgu Berk , Shnorhavorian Margarett , Braga Luis , Ernst Andreas , Lucas-Herald Angela , O'Toole Stuart , Faisal Ahmed S. , F. Rawashdeh Yazan

Background: Heterogeneity in reported outcomes limits the ability to compare results of studies evaluating hypospadias surgery.Objective: To identify a core outcome set (COS), a minimal number of defined outcomes, to be routinely measured and reported in all trials across the age span following hypospadias surgery.Materials and Methods: A study protocol was drafted and the study re...

hrp0095rfc6.4 | Sex Development and Gonads | ESPE2022

Sertoli cell dysfunction at diagnosis in children with haematological malignancies

Lopez Dacal Jimena , Prada Silvina , Gabriela Ropelato Maria , Gabriela Ballerini Maria , Eugenia Rodriguez Maria , E. Gutierrez Marcela , Soria Marcela , Morán Lorena , Ferraro Cristina , Bedecarrás Patricia , Drelichman Guillermo , Aversa Luis , Bergadá Ignacio , A. Rey Rodolfo , P. Grinspon Romina

Aim: To determine Sertoli cell function at diagnosis and after 3 months of chemotherapy.Methods: A prospective cohort study was performed including children with acute lymphoblastic leukaemia, acute myeloid leukaemia, or non-Hodgkin lymphoma. Serum levels of AMH were evaluated at diagnosis and after 3 months during chemotherapy. Results were analysed as standard deviation scores according to pubertal stage and expressed ...

hrp0095p1-49 | Diabetes and Insulin | ESPE2022

Impact of Metabolic-associated fatty liver disease (MAFLD) on the Cholesterol efflux capacity of High-density lipoproteins in adolescents with type 2 Diabetes

Antonio Orozco-Morales Jose , Torres-Tamayo Margarita , X. Medina-Urrutia Aida , Dies-Suárez Pilar , Méndez-Sánchez Nahum , Enrique Díaz-Orozco Luis , G. Medina-Bravo Patricia

Background: Type 2 diabetes (T2D) is an emerging disease in the pediatric population. T2D is associated with metabolic-associated fatty liver disease (MAFLD). High-density lipoproteins (HDLs) are lipoproteins that are believed to have atheroprotective properties that reduce the risk of cardiovascular disease (CVD). Current evidence suggests that the physicochemical and functional features of HDLs may play a key role in the pathogenesis of atherosclerosis.<...

hrp0092p1-331 | Diabetes and Insulin (2) | ESPE2019

Design and Implementation of an Integral System of Clinical Follow-Up and Glucose Monitoring in Children Affected of Type 1 Diabetes, in Andalusia

Hernández-Soto Rocío , Luque-Romero Luis , Alcaide-Gantes Alvaro , Mayoral-Sanchez Eduardo , Romero M del Mar , Dube Juan De Dios , Llamas-Porras Salvador , Sanchez-Laguna Francisco , Antonio Gomez-Palomeque Juan , Martinez-Brocca Asuncion

Introduction: The incorporation of the interstitial glucose monitoring system, in the offer of services in the Andalusian Public Health System (APHS), means an opportunity for the implementation of a model of integration, and follow-up of glucose data, and the evaluation of their impact in health results.Purpose (Aim): The design and implantation of a model that allows the identification, registration of clinical data, i...

hrp0092p2-118 | Fat, Metabolism and Obesity | ESPE2019

Impact of a Comprehensive Program, on Prevalence of Childhood Obesity in Andalusia, Spain

Hernández-Soto Rocio , Saenz-Lussagnet Juan Manuel , Luque-Romero Luis Gabriel , Alcaide-Gantes Alvaro , Reina-Ceballos Inmaculada , Sicre-Alonso Silvia , Reales-Arroyo Ana Maria , Gil-Barcenilla Begoña

Introduction: Childhood obesity means a Public Health problem. It is related to chronic diseases in adults, a decrease in quality of life, and an increase in social and sanitary costs. In Spain, the National Health Service (ENSE 2017) stood the prevalence of overweight in toddler between 2 to 7 years old, in 18,26% and obesity in 10,30%, no differences between sex. In 2015 the prevalence of overweight and obesity in childhood are 21, 3 % and 6, 2 &...

hrp0092p3-119 | Fat, Metabolism and Obesity | ESPE2019

ESPE 2019. Physical Activity, Food and Metabolic Risk in Children and Adolescents

de Lamas Carmela , Vázquez Rocío , José Bedoya Juan , Aguilera Concepción , Gil-Campos Mercedes , Bueno Gloria , Moreno Luis , Gil Ángel , Leis Rosaura

Introduction:The incidence of obesity increases unstoppably in all populations and at all ages, and with it, the associated metabolic morbidity and mortality. The promotion of physical activity and a healthy diet are the fundamental elements to alleviate this situation. The objective of this study is to determine the relationship of physical activity and eating patterns with body composition, the degree of adiposity and certain metabolic risk factors.<p cl...

hrp0089p3-p146 | Fat, Metabolism and Obesity P3 | ESPE2018

Does the Level of Studies of Parents Influence the Follow-up of the Recommendations of the Nutritional Pyramid?

Rosaura Leis Trabazo Maria , de Lamas Perez Carmela , Vazquez Cobela Rocio , Jose Bedoya Carpente Juan , Olza Meneses Josune , Gil Hernandez Angel , Alberto Moreno Aznar Luis , Bueno Lozano Gloria , Gil Campos Mercedes , Aguilera Garcia Concepcion

Introduction: Several studies show the negative impact of low level of studies of parents on the dietary patterns and the degree of adiposity of their children. The objective of this study is to evaluate the relationship between the level of studies and compliance with the recommendations of healthy eating pyramid.Material and method: An anthropometric study was conducted in 895 Spanish children and adolescents (53% women), between 3 and 18 years old (10...