hrp0094p2-224 | Fat, metabolism and obesity | ESPE2021

Inflammation associated to body composition in European prepubertal children: Results from the IDEFICS study

Argente Pilar , Esther Gonzalez , Intemann Timm , Moreno Luis , Molnar Denes , Kaprio Jaakko , Russo Paola ,

Background: Obesity is characterised by excessive fat accumulation coursing with a chronic mild inflammatory state, with adipose tissue (AT) being the main site of increased systemic cytokine production. Increased adiposity early in life is the main risk factor for cardiometabolic disorders later in life, with the abnormal accumulation of lipids in AT leading to the production of pro-inflammatory cytokines. Inflammatory process that involves metabolic and card...

hrp0092p1-33 | Diabetes and Insulin | ESPE2019

Plasma Tocopherols and Carotenes are Decreased in Spanish Children and Adolescents with Insulin Resistance, Independently of Obesity

Rupérez Azahara I. , Lozano Gloria Bueno , Leis Rosaura , Gil-Campos Mercedes , Gil Ángel , Moreno Luis A. , Mesa María D. , Aguilera Concepción M.

Introduction: Childhood obesity and insulin resistance (IR) are rising in prevalence, increasing the future adults' cardio-metabolic risk. One of the potential mechanisms behind these alterations is oxidative stress, fruit of increased free radical production and diminished antioxidant defense. Although low plasma vitamin concentrations and oxidative stress have been observed to be associated with obesity in adults and children, their association with IR i...

hrp0089p2-p129 | Fat, Metabolism and Obesity P2 | ESPE2018

Early-Life Risk Factors and Their Association with Hypertension in Spanish Children and Adolescents

Perez-Gimeno Gloria , Ruperez Azhara I , Gil-Campos Mercedes , Leis Rosaura , Aguilera Concepcion M , Gil Angel , Moreno Luis A , Bueno-Lozano Gloria

Introduction: In the last years, the prevalence of high blood pressure (HBP) has increased in children, contributing to raise the risk of future cardiovascular disease. It is known that family history, pregnancy characteristics and type of feeding in the first months of life are of great importance in the prevention of diseases in the offspring. In this study we aimed to investigate the association between early life risk factors and HBP in children and adolescents.<p clas...

hrp0086p1-p464 | Fat Metabolism and Obesity P1 | ESPE2016

Central Obesity among European Preschool Children: The ToyBox-Study

Galcheva Sonya , Lateva Mina , Iotova Violeta , Androutsos Odysseas , Manios Yannis , De Bourdeaudhuij Ilse , Cardon Greet , Socha Piotr , Moreno Luis , Koletzko Berthold , on behalf of ToyBox-Study Group

Background: Waist circumference (WC) reflects the fat distribution and the degree of central adiposity in children, which is specifically associated with cardiovascular risk factors and useful as a component of metabolic syndrome definition in children.Objective and hypotheses: To evaluate the distribution of WC measures among preschool children aged 3.5–5.5 years from six European countries.Method: Cross-sectional study of a ...

hrp0084p1-51 | Diabetes | ESPE2015

Distribution of Obesity Indices Among European Preschool Children and Associated Risk Factors: The ToyBox-Study

Galcheva Sonya , Lateva Mina , Iotova Violeta , Bourdeaudhuij Ilse De , Cardon Greet , Androutsos Odysseas , Kulaga Zbigniew , Socha Piotr , Moreno Luis , Koletzko Berthold , Manios Yannis , Group ToyBox-study

Background: Childhood obesity is a serious health problem, related to an increased risk of adult morbidity and mortality. Evidence indicates that central adiposity increases this risk to a higher degree compared to the general obesity indices.Objective and hypotheses: To evaluate the distribution of anthropometric obesity indices among preschool children aged 3.5–5.5 years, from six European countries, and to examine their associations with certain ...

hrp0092p3-119 | Fat, Metabolism and Obesity | ESPE2019

ESPE 2019. Physical Activity, Food and Metabolic Risk in Children and Adolescents

de Lamas Carmela , Vázquez Rocío , José Bedoya Juan , Aguilera Concepción , Gil-Campos Mercedes , Bueno Gloria , Moreno Luis , Gil Ángel , Leis Rosaura

Introduction:The incidence of obesity increases unstoppably in all populations and at all ages, and with it, the associated metabolic morbidity and mortality. The promotion of physical activity and a healthy diet are the fundamental elements to alleviate this situation. The objective of this study is to determine the relationship of physical activity and eating patterns with body composition, the degree of adiposity and certain metabolic risk factors.<p cl...

hrp0082p3-d2-781 | Fat Metabolism &amp; Obesity (1) | ESPE2014

Relationship Between Adiposity Degree and Physical Activity and Inactivity Among Children and Adolescents

Leis Rosaura , Vazquez-Cobela Rocio , Bedoya Juan Jose , Seoane Luisa Maria , Barja-Fernandez Silvia , Aguilera Concepcion , Olza Josune , Bueno Gloria , Gil-Campos Mercedes , Castro-Feijoo Lidia , Moreno Luis , Gil Angel , Tojo Rafael

Introduction: The highest prevalence of children and adolescents with obesity in Europe is observed in the south countries. This epidemic is related to unhealthy eating patterns, decreased physical activity and increased inactivity.Objective: To determine the relationship between adiposity degree and physical activity and inactivity in children and adolescents.Methods: 338 children from 6 to 8 years of age (x=11.11 years);...

hrp0084p3-887 | Fat | ESPE2015

Sports Regulated and Lipid Profile in Children and Adolescents with Overweight

Trabazo Rosaura Leis , Cobela Rocio Vazquez , Garcia Concepcion Aguilera , Lozano Gloria Bueno , Meneses Josune Olza , Campos Mercedes Gil , Carpente Juan Jose Bedoya , Feijoo Lidia Castro , Aznar Luis Moreno , Hernandez Angel Gil

Introduction: Obesity is the most common nutritional disorder in the paediatric age. Decreased physical activity and increased inactivity are important factors that are involved in this pandemic. The highest prevalence of obesity in Europe is in the South.Objective: To study the relationship between the practice of a regulated sport and lipid profile in overweight children and adolescents.Material and methods: 318 overweight childr...

hrp0094p2-122 | Diabetes and insulin | ESPE2021

Parental insulin resistance is associated with unhealthy lifestyle behaviours independently of body mass index in children: The Feel4Diabetes study

Gonzalez-Gil Esther M. , Gimenez-Legarre Natalia , Cardon Greet , Mavrogianni Christina , Kivela Jemina , Iotova Violeta , Tankova Tsvetalina , Imre Rurik , Liatis Stavros , Makrilakis Konstantinos , Schwarz Peter , Timpel Patrick , Dupont Elisabeth , Couck Pedro , Manios Yannis , Moreno Luis ,

Introduction and aim: Parental health is associated with children’s health and lifestyles. Thus, the aim of the present study was to assess lifestyle behaviours of children from parents with insulin resistance (IR) and at risk of type 2 diabetes.Methods: 2117 European parents from six countries included in the Feel4Diabetes-study measured in 2015 and identified as being at risk for diabetes with the FINDRISC questio...

hrp0092p1-345 | Fat, Metabolism and Obesity (2) | ESPE2019

ANGPTL-4 in Children and Adolescents: Relation to Gender, Puberty and Obesity

Barja-Fernández Silvia , Folgueira Cintia , Castelao Cecilia , Pena-León Verónica , González-Saenz Patricia , Vázquez-Cobela Rocío , Aguilera Concepción M , Gil-Campos Mercedes , Bueno Gloria , Gil Ángel , Moreno Luis , Ruiz-Piñon Manuel , García-Palacios María , Casanueva Felipe F , Dieguez Carlos , Nogueiras Rubén , Seoane Luisa M. , Leis Rosaura

Introduction: Preclinical models demonstrated that Angiopoietin-like protein 4 (ANGPTL-4) regulates lipid metabolism and affects energy homeostasis. However, no data exist regarding its involvement in childhood and adolescence, periods of life with important metabolic changes.Objectives: We aimed to investigate circulating levels of ANGPTL-4 in children and adolescents and its relationship with gender, puberty and obesit...