ESPE Abstracts

5-alpha-reductase is an enzyme for converting testosterone to dehydrotestestrone (DHT). A five-month-old infant with a karyotype of 46 XY and female genitalia referred to endocrinology clinic. Regarding the presence of Down syndrome in the family medical history, her mother had amniocentesis during pregnancy. The amniocentesis mentioned xy karyotype. However, repeated ultrasounds mentioned female genitalia. After birth, at 5 months, a first ultrasound mentioned no testis but s...

Background: Obesity is a disease (2) which is associated with increased morbidity and mortality rate (3) and needs extensive preventive procedures and effective interferences. Children with obese parent are in danger of becoming obese in their adolescence and adulthood even when trying to keep their weight stable.Objective and hypotheses: We aimed to investigate whether parental obesity can trigger obesity in children or not.Method...

Background: Obesity is a disease which is associated with increased morbidity and mortality rate and needs extensive preventive procedures and effective interferences. Children with obese parent are in danger of becoming obese in their adolescence and adulthood even when trying to keep their weight stable.Objective and hypotheses: We aimed to investigate whether parental obesity can trigger obesity in children or not.Method: This i...

Background: Thallassemia is a genetic disease with recessive autosomal pattern of inheritance which occurs as a result of disorders in hemoglobin structure clinicians assess endocrine function in patients with thallassemia in various intervals and distinguishing appropriate time for assessment can decrease the mentioned complications and promote their health.Objective and hypotheses: We aimed to investigate the prevalence of hypothyroidism and the relati...

Background: Thallassemia is a genetic disease with recessive autosomal pattern of inheritance which occurs as a result of disorders in hemoglobin structure clinicians assess endocrine function in patients with thallassemia in various intervals and distinguishing appropriate time for assessment can decrease the mentioned complications and promote their health, we aimed to investigate the prevalence of hypothyroidism and the relation between thyroid hormones and ferritin in pati...

Background: Short stature is a common problem in children. This study aimed to determine the cause of short stature in children in Rasht is 2–15 years.Methods: This study was done on 148 children aged 2–15 years with short stature in 2008–2011 shorter 17 Shahrivar patients have been conducted. Demographic characteristics of children, child, and family history of the disease, blood tests, hormone stimulation test growth, physical examinatio...

Introduction and Aims: Metabolic syndrome (METs) has different complications such as cardiovascular diseases and diabetes type 2. There is no uniform definition for METs. In this study, we aimed to define METs from different viewpoints to determine the most appropriate method that could be used for early METs diagnosis in general population and treat them immediately.Materials and Methods: This study was an analytic cros...

5-alpha reductase converts testosterone to dihydrotestostrone. SRD5A2 mutation leading to deficiency of 5-alpha reductase causes a disorder of 46,XY sex development named 5-alpha reductase type 2 deficiency. Due to deficit of this enzyme, female external genitalia is common sign of disease in 46,XY individuals. SRD5A2 mutations have been reported in different ethnicities. Here, mutations of this gene are reported in Iranian subjects. Affected individuals were subjected to stud...

Aim: The aim of this study was to evaluate hematological indices especially PLT indices in children with T1DMMaterials and Methods: in this case-control study which was conducted on 166 participants including 83 children with diabetes type 1 and 83 children hospitalized for thorough assessment of short stature, PLT count, MPV, PDW, WBC count, hemoglobin, blood sugar,PCT, P-LCR, ans PLR were assessed. Patients with type 1...

Background: Recent studies had been demonstrated that raised height could be related with Hodgkin lymphoma (HL). In addition, increased osteo–sarcorma had been indicated in taller individuals and those with earlier pubertal growth spurts. however, some investigators obtained no significant relation between elevated height and childhood malignancy.Objective and hypotheses: We aimed to investigate whether there is any correlation between height and pe...