hrp0092p3-280 | Late Breaking Abstracts | ESPE2019

Short, but Daily and Controlled Physical Activity of Children with Obesity has a Positive Effect on The Irisin and Chemerin Levels

Wójcik Małgorzata , Kozioł-Kozakowska Agnieszka , Januś Dominika , Furtak Aleksandra , Starzyk Jerzy

Therapeutic interventions in obesity in addition to the weight loss, seek to improve the profile of cytokines. It is believed that physical activity, even in the absence of significant weight loss, may favorably increase the concentration of irisin and decrease the concentration of chemerin. The aim of the study was to compare the impact of a standard lifestyle intervention (SI) with an intense intervention (II) including controlled increase of daily physical ...

hrp0082p1-d1-201 | Reproduction | ESPE2014

The Effect of 17β-Estradiol on Uterine Volume in Young Women with Turner Syndrome: a 5-Year Randomized Controlled Clinical Trial

Cleemann Line , Holm Kirsten , Fallentin Eva , Moller Nini , Kristensen Bent , Skouby Sven Oluf , Leth-Esbensen Per , Jeppesen Eva Mosfeldt , Gravholt Claus

Background: The majority of Turner syndrome (TS) girls need exogenous estrogen treatment to induce normal uterine growth. The optimal estrogen treatment protocol has not been determined.Objective and hypotheses: To compare the effect of two different dosing regimens of oral 17β-estradiol on uterine size with the hypotheses that most girls with TS would benefit from a higher dose.Method: A double-blind 5-year randomized control...

hrp0089p2-p162 | Fat, Metabolism and Obesity P2 | ESPE2018

Correlation of Dietary Habits with Systolic Blood Pressure in Healthy Children

Efthymia Katsa Maria , Batsikoura Maria , Dolianiti Loukia , Vasilopoulos Vasileios , Eleni Kougioumtzi Dimoliani Dafni , Dimopoulos Ioannis , Paola Rojas Gil Andreea

Background: Pediatric hypertension is a risk factor for adult hypertension and cardiovascular disease which entails the necessity of early detection.Aim: To investigate how nutrition habits are correlated with systolic blood pressure (SBP) in health children and adolescent population.Methods: 1395 children and adolescents from Greece were enrolled to participate in the research. A specially designed questionnaire regarding to eatin...

hrp0084p3-867 | Fat | ESPE2015

Insulin Resistance in Adolescents with Screen Addiction and Attention-Deficit/Hyperactivity Disorder

Koprulu Ozge , Darcan Sukran , Ozbaran Burcu , Ata Emsal , Altinok Yasemin , Ozen Samim , Goksen Damla

Background: Screen (TV, tablet, smartphones, internet, video games, PC etc.) addiction is a growing problem in child health. The effect on insulin-glucose metabolism is not well known yet.Objective and hypotheses: To investigate the insulin resistance in screen addicted children.Method: We studied 108 children and adolescents aged 13.72±1.95 years (range 11–17 years). Participants were divided into three groups according ...

hrp0094p2-189 | Fat, metabolism and obesity | ESPE2021

Prospective evaluation of liver stiffness in obese children: the role of shear wave elastography.

Corica Domenico , Bottari Antonio , Aversa Tommaso , Anna Morabito Letteria , Curatola Selenia , Alibrandi Angela , Ascenti Giorgio , Wasniewska Malgorzata ,

Objectives: The increased incidence of childhood obesity and related non-alcoholic fatty liver disease (NAFLD) has determined the need to identify a non-invasive technique to diagnose and monitor NAFLD. Two-dimensional shear wave elastography (2D-SWE) has emerged as a reliable, non-invasive, tool to evaluate liver tissue elasticity in clinical practice. Aims of this study were to longitudinally evaluate 2D-SWE changes in relation to weight loss, metabolic prof...

hrp0098p3-193 | Pituitary, Neuroendocrinology and Puberty | ESPE2024

Height Gain after GnRH agonist Treatment for Precocious Puberty or Early Puberty

Hyang Cho Ja , Woon Jung Hae , Shik Shim Kye

Purpose: Gonadotropin-releasing hormone (GnRH) analog is the first-line treatment with precocious puberty happens before age 8 in girls. This study is aim ed to investigate the relationship between height gain and other factors, specifically to analyze validated tool for predicting adult height for precocious puberty or early puberty.Method: From January 2022 to June 2022, 32 girls with central precocious puberty who vis...

hrp0097p1-542 | Pituitary, Neuroendocrinology and Puberty | ESPE2023

Comparation between syndromic and non-syndromic central precocious puberty: a 10-year experience

Assirelli Valentina , Ortolano Rita , Baronio Federico , Di Natale Valeria , Cantarelli Erika , Bernardini Luca , Cassio Alessandra

Introduction: Central Precocious Puberty (CPP) has recently been described in patients with isolated or syndromic neurodevelopmental disorders, with greater attention from the scientific community. We carried out this study to compare the main aspects of non-isolated and isolated forms of CPP.Methods: We conducted a retrospective monocentric study, collecting all treated cases of CPP from 1st January 2013 to 31 December ...

hrp0097p2-257 | Late Breaking | ESPE2023

A cohort study on growth hormone therapy in Chinese children with Prader-Willi syndrome – the effect of treatment age

Zho Qiong , Zou Chaochun

Background: Prader-Willi syndrome (PWS) is a rare multisystemic genetic disorder. Recombinant human growth hormone (rhGH) therapy is the most established form of treatment for PWS. This study aimed to investigate the effect of rhGH treatment age on the treatment outcome of children with PWS.Methods: A retrospective analysis of 167 genetically confirmed Chinese children with PWS followed between 2017 and 2022. Unadjusted ...

hrp0089p1-p103 | Fat, Metabolism and Obesity P1 | ESPE2018

Associations of Non-High-Density Lipoprotein Cholesterol with Metabolic Syndrome and Its Components in Korean Children and Adolescents: the Korea National Health and Nutrition Examination Surveys 2008–2014

Shim Young Suk , Jeong Hwal Rim , Yang Seung , Kim Eun Young , Hwang Il Tae

Background: In this study, we aimed to investigate the relationship between single-gender Korean references for non-high-density-lipoprotein cholesterol (non-HDL-C) and metabolic syndrome (MetS) in childhood.Methods: A total of 5,742 Korean children aged 10–18 years who participated in a national survey were included. The subjects were classified into three groups based on single-gender non-HDL-C levels as follows: <120 mg/dl (desirable), &#8805...

hrp0082p2-d1-535 | Puberty and Neuroendocrinology | ESPE2014

Correlation Research of Bisphenol A and Premature Thelarche in 6 Months to 2 Years Old Infant Girls

Wu Haiying , Chen Linqi , He Guangzhao , Wang Weipeng

Background: Now in many causes of precocious puberty, thinking of environmental endocrine disruptors (EDCs) is one of the causes. Bisphenol A (BPA), as a kind of environmental endocrine disruptors, can interfere with normal endocrine activities. But up to now, there is few reports of the influence of BPA in premature thelarche (PT) of below 2 years girls.Objective and hypotheses: To investigate the association between BPA and premature thelarche in 6 mon...