ESPE Abstracts

ESPE Abstracts

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hrp0094p1-38 | Fat, Metabolism and Obesity A | ESPE2021

Are Serum Spexin Levels Associated With Metabolic Syndrome Antecedents In Obese Adolescents?

Gulderen Kalay Şenturk Nida , Cakır Aydilek Dağdeviren , Yıldırmak Zeynep Yıldız , Ucar Ahmet ,

Objective: Spexin is a novel peptide implicated in food intake and satiety. Spexin levels are reduced in obese patients.Aim: To evaluate the associations of metabolic syndrome (metS) antecedents with serum spexin levels in obese adolescents.Setting: A university- based tertiary care centre.Patients and methods: Eighty consecutive obese adolescents aged 10-18 y and 80 healthy ...
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hrp0094p2-282 | Growth and syndromes (to include Turner syndrome) | ESPE2021

Brain-derived neurotrophic factor and matrix metalloproteinases as markers of metabolic status in girls with Turner syndrome.

Błaszczyk Ewa , Gawlik Jakub , Gieburowska Joanna , Tokarska Agnieszka , Francuz Tomasz , Gawlik Aneta ,

Background: Turner syndrome (TS) predisposes to obesity and related metabolic disorders and presents a high risk of congenital heart defects. Growth hormone (GH) treatment used in TS girls also affects the parameters of carbohydrate-lipid metabolism. Thus, the search for new markers that could be early predictors of metabolic disorders seems to be justified.Objective and Method: The assessment and comparison of MMP-1, MMP-2, MMP-9 (matri...
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hrp0092p1-333 | Diabetes and Insulin (2) | ESPE2019

Abdominal Fat Distribution Assessed by Abdominal CT Scan in Adolescents with Type 2 Diabetes Mellitus

Abe Yuriko , Urakami Tatsuhiko , Hara Mitsuhiko , Yoshida Kei , Mine Yusuke , Aoki Masako , Suzuki Junichi , Saito Emiko , Iwata Fujihiko , Okada Tomoo , Morioka Ichiro

Background: Abdominal fat distributions are reportedly strongly associated with metabolic risks in type 2 diabetes mellitus. However, research on fat distribution in adolescents with type 2 diabetes mellitus has been limited.Aim: To investigate fat distribution characteristics in adolescents with type 2 diabetes mellitus for comparison to those with simple obesity in Japan.Design/Methods</s...
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hrp0092p3-155 | Growth and Syndromes (to include Turner Syndrome) | ESPE2019

Turners Syndrome - Clinical Presentation, Genetics, Investigation and Management: A 10-Year Review

Elechi Hassan Abdullahi , Law James , Alexander Jacqui , Denvir Loiuse , Randell Tabitha , Sachdev Pooja

Background: Turner syndrome (TS) is characterised by a wide phenotype and age at presentation. We reviewed our over-12s Turner clinic over a period of 10 years to evaluate pattern of diagnosis, co-morbidities and management.Subjects & Method: Retrospective data analysis of patients with TS who attended the over-12s clinic (2008-2017, n=28). Data is median (IQR) or mean±SD as appropriate.<p class...
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hrp0086p1-p479 | Fat Metabolism and Obesity P1 | ESPE2016

Hepatic Steatosis and Cardiovascular Risk in Overweight Children: Preliminary Results of the Study EFIGRO

Diez-Lopez Ignacio , Sarasua Ainhoa , Medrano Maria , Arenaza Lyde , Rodriguez-Vigil Beatriz , Tobalina Ignacio , Larrarte Eider , Perez-Asenjo Javier , Labayen Idoia

Introduction: The accumulation of fat in the liver is a serious complication of childhood obesity seems to be associated with cardiometabolic risk.Objective: To examine the association between fat accumulation in the liver and cardiovascular risk factors in overweight children.Material and methods: In the study 68 children/as (51.4% girls) were overweight or obese (defined according to the classification criteria of the Internation...
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hrp0092p2-291 | Thyroid | ESPE2019

Investigation of Oxidative Effect in Saliva and Gingival Groove Fluids in Children with Hashimoto Thyroiditis

Atar Müge , Tan Aykut , Yetkin Ay Zuhal , Atar Müge , Pirgon Özgür

The aim of this study was to determine the periodontal health status in patients with Hashimoto thyroiditis (HT) and investigate the gingival groove fluid and saline oxidative stress parameters in order to demonstrate their relationship.Method: 30 patients between the ages of 11-17 years and 30 healthy volunteers aged between 10-17 years were included in the study. Serum tT4, TSH, anti-TPO, glucose, insulin, ALT, triglyceride, total chol...
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hrp0092p3-78 | Diabetes and Insulin | ESPE2019

Prevalence of Fatty Liver in Children with Type 1 Diabetes Mellitus Attending Diabetes Clinic of Alexandria University Children's Hospital

Mowafy Ehsan , Mahfouz Amel , El Neily Dalia , Ramzy Heba

Background: The non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. It is not uncommon in children with type 1 Diabetes Mellitus. It is often asymptomatic and discovered accidentally.Aim: The aim of this work was to screen the presence of fatty liver among children with type 1 DM attending the diabetes Clinic of Alexandria University Children's Hospital and its relation to the state ...
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hrp0082p3-d2-776 | Fat Metabolism &amp; Obesity (1) | ESPE2014

Prevalence of Dyslipidemia and Associated Factors Among Obese Turkish Children

Elmaogullari Selin , Tepe Derya , Ucakturk Ahmet , Demirel Fatma

Background: Obesity prevalence among children increased worldwide in last three decades. Childhood onset obesity is associated with increased mortality and morbidity related to cardiovascular diseases during adulthood. Dyslipidemia has a fundamental role in the pathogenesis of cardiovascular diseases.Objective and hypotheses: This study is designed to evaluate the prevalence and related factors of dyslipidemia among obese children and adolescent.<p c...
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hrp0084p3-885 | Fat | ESPE2015

Is vitamin D Important Player in Hepatosteatosis in Childhood Obesity?

Ozsu Elif , Topcu Feyza Nur , Tepe Derya Acar

Background and aim: Childhood obesity is one of the most serious public health problem. Obesity-related complications such as hepatic steatosis or type 2 diabetes can now be monitored even during early childhood. The aim of the study was to examine the relationship between vitamin D levels and obesity with hepatosteatosis (HS) in children.Methods: A total of 128 children with obesity were included in this study. HS was diagnosed using ultrasonography. HS...
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hrp0095t12 | Section | ESPE2022

Assessment of non-alcoholic fatty liver disease with non-invasive indices in adolescents with polycystic ovary syndrome

Context: Polycystic ovary syndrome (PCOS) is a complex disorder affecting women from adolescence until menopause. PCOS in adolescent years shares common features with clinical presentation in adulthood, including the adverse metabolic profile. Non-alcoholic fatty liver disease (NAFLD) is a spectrum of hepatic changes, from liver steatosis to severe inflammation and fibrinogenesis.Objective: To assess NAFLD in an adolesce...
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